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1.发明授权RECOMBINANT IL-5 ANTAGONISTS USEFUL IN TREATMENT OF IL-5 MEDIATED DISORDERS 失效重组IL-5拮抗剂，IL-5相关的疾病治疗
公开(公告)号：EP0800536B1
公开(公告)日：2006-11-29
申请号：EP95944692.3
申请日：1995-12-22
发明人： AMES, Robert S. , APPELBAUM, Edward Robert , CHAIKEN, Irwin M. , COOK, Richard M. , GROSS, Mitchell Stuart , HOLMES, Stephen Dudley , McMILLAN, Lynette Jane , THEISEN, Timothy Wayne
IPC分类号： C07K16/24 , C12N5/20 , C07K19/00 , C12N15/13 , A61K39/395 , A61P11/06 , A61P37/08 , A61P17/00 , C12N15/85 , G01N33/68
CPC分类号： C07K16/244 , A61K38/00 , A61K2039/505 , C07K14/5409 , C07K14/7155 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C12N2799/026 , G01N33/6869
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2.发明授权
公开(公告)号：EP0730609B1
公开(公告)日：2005-01-05
申请号：EP94929191.8
申请日：1994-09-07
IPC分类号： C07K16/24 , C07K16/46 , C07K17/02 , C07H15/12 , G01N33/53 , C12P21/08 , C12N5/10 , C12N5/20 , C12N15/13 , A61K39/395
CPC分类号： C07K16/247 , A61K38/00 , C07K2317/24 , C07K2317/34 , C07K2319/00 , G01N33/6869
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3.发明公开RECOMBINANT IL-5 ANTAGONISTS USEFUL IN TREATMENT OF IL-5 MEDIATED DISORDERS 失效重组IL-5拮抗剂，IL-5相关的疾病治疗
公开(公告)号：EP0800536A2
公开(公告)日：1997-10-15
申请号：EP95944692.0
申请日：1995-12-22
发明人： AMES, Robert S. , APPELBAUM, Edward Robert , CHAIKEN, Irwin M. , COOK, Richard M. , GROSS, Mitchell Stuart , HOLMES, Stephen Dudley , McMILLAN, Lynette Jane , THEISEN, Timothy Wayne
IPC分类号： G01N33 , A61K39 , A61K45 , A61P11 , A61P17 , A61P37 , C07K14 , C07K16 , C12N5 , C12N15 , C12P21 , A61K38
CPC分类号： C07K16/244 , A61K38/00 , A61K2039/505 , C07K14/5409 , C07K14/7155 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C12N2799/026 , G01N33/6869
摘要： Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
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4.发明公开
公开(公告)号：EP0730609A1
公开(公告)日：1996-09-11
申请号：EP94929191.0
申请日：1994-09-07
CPC分类号： C07K16/247 , A61K38/00 , C07K2317/24 , C07K2317/34 , C07K2319/00 , G01N33/6869
摘要： Chimeric and humanized IL4 MAbs derived from high affinity MAbs, pharmaceutical compositions containing same, and methods of treatment are provided.
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5.发明公开NOVEL ANTIBODIES FOR CONFERRING PASSIVE IMMUNITY AGAINST INFECTION BY A PATHOGEN IN HUMANS 失效被动免疫SUPPLIED通过抗体对致病HERVORGERUFENDE的人类感染。
公开(公告)号：EP0659192A1
公开(公告)日：1995-06-28
申请号：EP93921412.0
申请日：1993-09-08
申请人： SMITHKLINE BEECHAM CORPORATION , THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY , THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE ARMY
发明人： GROSS, Mitchell Stuart , ROSENBERG, Martin , SADOFF, Jerald, Charles , HOFFMAN, Stephen , SYLVESTER, Daniel, R. , CHAROENVIT, Yupin , HURLE, Mark,
CPC分类号： C07K16/205 , A61K38/00 , A61K39/00 , C07K2319/02 , Y02A50/412
摘要： Proteins and peptides derived from a murine (P. falciparum) monoclonal antibody, including synthetic humanized variable light chain and variable heavy chain sequences, CDR peptides, and humanized antibodies useful in therapeutic methods and compositions for conferring passive immunity to infection by a malaria-causing parasite are provided.
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