-
公开(公告)号：EP0451869A3
公开(公告)日：1992-07-08
申请号：EP91105883.2
申请日：1991-04-12
IPC分类号： A61K31/565 , C07J1/00
CPC分类号： C07J1/0011
摘要： A remedy for endometriosis comprising, as an active ingredient, 14a-hydroxy-4-androstene-3,6,17-trione or an ester derivative thereof, can effectively treat endometriosis by the strong aromatase-inhibitory activity without giving serious side effects.
-
2.发明公开Process for preparing 14-alpha-hydroxy-4-androstene-3,6,17-trione 失效制备14-ALPHA-羟基-4-安慰剂-3,6,17-TRIONE的方法
公开(公告)号：EP0382162A3
公开(公告)日：1991-03-13
申请号：EP90102302.8
申请日：1990-02-06
IPC分类号： C07J1/00
CPC分类号： C07J1/0011
摘要： A process for the preparation, in high yield, of 14-α-hydroxy-4-androstene-3,6,17-trione which has an aromatase inhibition activity and is useful as an antitumor agent, in which a hydroxyl group at position 6-β of 6-β,14-α-dihydroxy-4-androstene-3,17-dione is selectively oxidized with the aid of light energy.
-
公开(公告)号：EP0612742A1
公开(公告)日：1994-08-31
申请号：EP94301253.4
申请日：1994-02-22
发明人： Hoshino, Tsutomu , Kimura, Kenichi , Takahashi, Hidetoshi , Uchiyama, Takeo , Yoshihama, Makoto
IPC分类号： C07D403/14 , A61K31/40 , C12P17/16
CPC分类号： C07D403/14 , C12P17/165
摘要： A physiologically active compound having the following chemical structure is disclosed. This compound is prepared by culturing Chromobacterium violaceum, adding tryptophan and diethyldithiocarbamate (diethyldithiocarbamic acid) to the culture broth for reacting with the cells for producing it in the cells, and collecting the compound from the culture broth. This novel compound possesses antitumor and antimicrobial activity, and is effective as an antitumor agent or an antimicrobial agent.
摘要翻译： 公开了具有以下化学结构的生理活性化合物。 通过培养色素杆菌（Chromobacterium violaceum），将色氨酸和二乙基二硫代氨基甲酸酯（二乙基二硫代氨基甲酸）加入到培养肉汤中与细胞反应以在细胞中生产，并从培养液中收集化合物来制备该化合物。 该新型化合物具有抗肿瘤和抗菌活性，作为抗肿瘤剂或抗微生物剂有效。
-
4.发明公开Use of steroid derivatives in the treatment of endometriosis 失效Verwendung von Steroidderivaten zur Behandlung der Endometriose。
公开(公告)号：EP0451869A2
公开(公告)日：1991-10-16
申请号：EP91105883.2
申请日：1991-04-12
IPC分类号： A61K31/565 , C07J1/00
CPC分类号： C07J1/0011
摘要： A remedy for endometriosis comprising, as an active ingredient, 14a-hydroxy-4-androstene-3,6,17-trione or an ester derivative thereof, can effectively treat endometriosis by the strong aromatase-inhibitory activity without giving serious side effects.
摘要翻译： 含有14α-羟基-4-雄甾烯-3,6,17-三酮或其酯衍生物作为活性成分的子宫内膜异位症的治疗方法可以通过强烈的芳香酶抑制活性有效治疗子宫内膜异位症，而不会产生严重的副作用。
-
5.发明授权Process for preparing 14-alpha-hydroxy-4-androstene-3,6,17-trione 失效一种用于14-α-羟基-4-雄甾烯-3,6,17-，三酮的制备过程。
公开(公告)号：EP0382162B1
公开(公告)日：1994-06-22
申请号：EP90102302.8
申请日：1990-02-06
IPC分类号： C07J1/00
CPC分类号： C07J1/0011
-
6.发明授权
公开(公告)号：EP0391503B1
公开(公告)日：1994-06-15
申请号：EP90201279.8
申请日：1988-02-05
CPC分类号： C12P33/06 , C07J7/002 , C07J7/0045
-
7.发明公开
公开(公告)号：EP0391503A3
公开(公告)日：1991-01-30
申请号：EP90201279.8
申请日：1988-02-05
CPC分类号： C12P33/06 , C07J7/002 , C07J7/0045
摘要： 7β-hydroxy-4-pregnene-3,20-dione derivatives are prepared by use of Acremonium sp. The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themselves have also cell differentiaition activity for Ml cells.
-
公开(公告)号：EP0451869B1
公开(公告)日：1995-12-27
申请号：EP91105883.2
申请日：1991-04-12
IPC分类号： A61K31/565 , C07J1/00
CPC分类号： C07J1/0011
-
公开(公告)号：EP0556482A3
公开(公告)日：1994-01-05
申请号：EP92121791.5
申请日：1992-12-22
CPC分类号： A61K38/005 , C07K7/52
摘要： A prolyl endopeptidase inhibitor, antiamnesia agent, AIDS treating agent, or anti-HIV agent, comprising a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof.
摘要翻译： 一种脯氨酰内肽酶抑制剂，抗精神病剂，AIDS治疗剂或抗HIV剂，其包含由下式（I）表示的化合物或其药学上可接受的盐。
-
10.发明公开Preparation of 7 beta-hydroxy-4-pregnene-3,20-dione derivatives 失效Herstellung von 7-β-Hydroxy-4-pregnancyen-3,20-dion-Derivaten。
公开(公告)号：EP0391503A2
公开(公告)日：1990-10-10
申请号：EP90201279.8
申请日：1988-02-05
CPC分类号： C12P33/06 , C07J7/002 , C07J7/0045
摘要： 7β-hydroxy-4-pregnene-3,20-dione derivatives are prepared by use of Acremonium sp.
The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themselves have also cell differentiaition activity for Ml cells.摘要翻译： 7β-羟基-4-孕烯-3,20-二酮衍生物通过使用Acremonium sp。 这些化合物的一组可能被用作合成具有排卵抑制活性的孕酮衍生物的中间体。 这些化合物本身也具有对M1细胞的细胞分化活性。
-
-
-
-
-
-
-
-
-
搜索结果
13 条记录 (耗时 0.009 秒)
