METHOD FOR PRODUCING PYRAZOLE COMPOUND
    2.
    发明公开
    METHOD FOR PRODUCING PYRAZOLE COMPOUND 有权
    VERFAHREN ZUR HERSTELLUNG EINER PYRAZOLVERBINDUNG

    公开(公告)号:EP3112350A4

    公开(公告)日:2017-08-09

    申请号:EP15755927

    申请日:2015-02-16

    IPC分类号: C07D231/22 C07D231/20

    CPC分类号: C07D231/22 C07D231/20

    摘要: A method for producing a pyrazole compound represented by formula (1): (wherein R 1 represents an optionally substituted C 1-12 alkyl group, an optionally substituted C 3-12 cycloalkyl group, an optionally substituted C 6-16 aryl group, or an optionally substituted pyridyl group, R 2 and R 3 each independently represent a hydrogen atom, a halogen atom, a C 1-3 alkyl group, or a C 1-3 haloalkyl group), said method including a step in which a pyrazolidine compound represented by formula (2): (wherein R 1 , R 2 , and R 3 are as defined above) is reacted with a nitrite in the presence of an acid, allows a pyrazole compound to be produced industrially.

    摘要翻译: 式(1)所示的吡唑化合物的制造方法,式中,R 1表示可以具有取代基的C 1-12烷基,可以具有取代基的C 3-12环烷基,可以具有取代基的C 6-16芳基或 任选取代的吡啶基,R 2和R 3各自独立地表示氢原子,卤素原子,C 1-3烷基或C 1-3卤代烷基),所述方法包括以下步骤:将吡唑烷化合物 (2)表示的化合物:(其中R 1,R 2和R 3如上定义)与亚硝酸盐在酸存在下反应,允许工业生产吡唑化合物。