专利检索 ap:("Sangamo BioSciences, Inc." OR "The Regents of the University of California") AND inv:"MCCAMMON, Jasmine" 第 1 页

1.

发明公开
GENOMIC EDITING IN ZEBRAFISH USING ZINC FINGER NUCLEASES 审中-公开
标题翻译：斑马鱼的基因组编辑使用锌指核酸酶

公开(公告)号：EP2205729A2

公开(公告)日：2010-07-14

申请号：EP08833574.0

申请日：2008-09-25

申请人： Sangamo BioSciences, Inc. , The Regents of the University of California

发明人： AMACHER, Sharon , DOYON, Yannick , MCCAMMON, Jasmine , URNOV, Fyodor

IPC分类号： C12N9/22 , C07K19/00 , A01K67/027 , C12N5/10 , C12N15/55 , C12N15/62

CPC分类号： A01K67/0276 , A01K2217/075 , A01K2227/40 , A01K2267/03 , C07K2319/00 , C07K2319/81 , C12N9/22 , C12N2800/80

摘要： Disclosed herein are methods and compositions for genomic editing of one or more genes in zebrafish, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.