公开(公告)号：EP2852662B1

公开(公告)日：2020-09-16

申请号：EP13793902.1

申请日：2013-05-21

申请人： Sanofi Pasteur Limited ,  Sanofi Pasteur Biologics, LLC

发明人： ANDERSON, Stephen ,  DELAGRAVE, Simon ,  HAMBERGER, John ,  LI, Qinglian ,  MUNDLE, Sophia ,  RAHMAN, Nausheen

IPC分类号： A61K39/12 ,  C12N7/00

公开(公告)号：EP2852662A2

公开(公告)日：2015-04-01

申请号：EP13793902.1

申请日：2013-05-21

申请人： Sanofi Pasteur Limited ,  Sanofi Pasteur Biologics, LLC

发明人： ANDERSON, Stephen ,  DELAGRAVE, Simon ,  HAMBERGER, John ,  LI, Qinglian ,  MUNDLE, Sophia ,  RAHMAN, Nausheen

IPC分类号： C12N7/00

摘要： The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.

公开(公告)号：EP3769082A1

公开(公告)日：2021-01-27

申请号：EP19771535.2

申请日：2019-03-19

申请人： Sanofi Pasteur Limited

发明人： AUSAR, Salvador Fernando ,  ROQUE, Cristopher ,  STRAHLENDORF, Kirsten April ,  RAHMAN, Nausheen

IPC分类号： G01N33/48 ,  G01N21/64 ,  G16C20/00 ,  G16B25/10