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    Topical product
    3.
    发明公开
    Topical product 有权
    Topisches Produkt

    公开(公告)号：EP2384741A2

    公开(公告)日：2011-11-09

    申请号：EP11003689.4

    申请日：2011-05-05

    申请人： Sarek, Jan ,  Ceské Vysoké Ucení Technické V Praze

    发明人： Sarek, Jan ,  Vlk, Martin

    IPC分类号： A61K8/63 ,  A61K8/97 ,  A61Q17/00 ,  A61Q19/00

    CPC分类号： A61K36/185 ,  A61K8/63 ,  A61K8/97 ,  A61K2236/37 ,  A61Q19/00

    摘要： A topical product is provided, which contains supercritical birch bark extract as an active component. The supercritical birch bark extract contains betulin and lupeol as main components. The topical product may further include auxiliary active components, such as tea tree oil, olive oil, camomile oil, allantoin and lanolin. It has a strong antiseptic, healing and regeneration effects.

    摘要翻译： 提供了含有超临界桦树皮提取物作为活性成分的局部产品。 超临界桦树皮提取物含有桦木醇和紫苏醇作为主要成分。 局部产品还可以包括辅助活性成分，例如茶树油，橄榄油，甘油，尿囊素和羊毛脂。 它具有很强的消毒，愈合和再生效果。

    RADIUM FOR RADIONUCLIDE THERAPY, IN COMBINATION WITH CALCIUM METABOLISM AFFECTING TREATMENT
    4.
    发明公开
    RADIUM FOR RADIONUCLIDE THERAPY, IN COMBINATION WITH CALCIUM METABOLISM AFFECTING TREATMENT 审中-公开

    公开(公告)号：EP3563875A1

    公开(公告)日：2019-11-06

    申请号：EP18170735.7

    申请日：2018-05-04

    申请人： Ceské vysoké ucení technické v Praze ,  UJV Rez, A.S.

    发明人： Kozempel, Ján ,  Vlk, Martin ,  Mi olová, Petra ,  Kukleva, Ekaterina ,  Jandová, Ludmila ,  Merhautová, Hana ,  Ficenzová, Karolína

    IPC分类号： A61K51/02 ,  A61K51/12

    摘要： The present invention relates to a set for radionuclide therapy, comprising a component A and a component B, for use in the treatment of bone diseases by administration of the component B in a dosage ensuring a higher than physiological concentration of a substance affecting Ca 2+ metabolism in the organism and/or in the compartment treated, and co-administration of the component A, wherein the component A comprises a water-soluble radium salt containing at least one radionuclide of radium, and the component B comprises at least one substance affecting Ca 2+ metabolism in the organism, selected from the group comprising water-soluble salts of alkaline earth metals, calciferols, calcitonins, thyroid and parathyroid gland hormones, amino acids and salts thereof, peptides having a chain length of 2 to 100 amino acids and salts thereof, bisphosphonates of the general formula (I),

    wherein R 1 is -H, -OH, -Cl;
    R 2 is -CH 3 , -Cl, -CH 2 CH 2 NH 2 , -(CH 2 ) 5 -NH 2 , -(CH 2 ) 3 -NH 2 ,

    CH 2 CH 2 N(CH 3 )-(CH 2 ) 4 CH 3 ;
    and combinations thereof.