专利检索 ap:("Schering Corporation") AND inv:"KNUTSON, Chad E." 第 1 页

1.

发明公开
AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM 审中-公开
标题翻译：氮杂环丁烷而且AZETIDONDERIVATE疼痛和脂类代谢疾病治疗

公开(公告)号：EP2066316A1

公开(公告)日：2009-06-10

申请号：EP07838156.3

申请日：2007-09-13

申请人： Schering Corporation

发明人： MCKITTRICK, Brian , SMITH, Elizabeth M. , BENNETT, Chad E. , BURNETT, Duane A. , KNUTSON, Chad E.

IPC分类号： A61K31/397 , C07D471/10 , C07D487/10 , A61K31/438 , A61P29/00

CPC分类号： C07D471/10 , C07D487/10

摘要： Disclosed are compounds of formula (I) wherein Z1 is -CH2- or -C(O)-, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5, and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclosed are methods of treating pain using a compound of formula (I).