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1.发明授权IMIDAZOLE DERIVATIVES AS FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS 有权咪唑衍生物alpha2C肾上腺素受体的功能性选择性激动剂
公开(公告)号：EP1945626B1
公开(公告)日：2011-07-27
申请号：EP06789950.0
申请日：2006-08-23
发明人： MCCORMICK, Kevin, D. , BOYCE, Christopher, W. , ASLANIAN, Robert, G. , SHIH, Neng-Yang , FEVRIER, Salem , MANGIARCINA, Pietro , HUANG, Chia-Yu , LIANG, Bo , LIU, Rong-Qiang , LU, Huagang
IPC分类号： C07D401/06 , C07D403/06 , A61K31/435 , A61K31/41 , A61P29/00
CPC分类号： C07D403/02 , C07D401/06 , C07D403/06
摘要： In its many embodiments, the present invention provides imidazole derivatives which are inhibitors of alPha2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition or amelioration of one or more conditions associated with the alpha2C adrenergic receptors using such compounds or pharmaceutical compositions. Formula (I).
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2.发明公开IMIDAZOLE DERIVATIVES AS FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS 有权咪唑衍生物alpha2C肾上腺素受体的功能性选择性激动剂
公开(公告)号：EP1945626A1
公开(公告)日：2008-07-23
申请号：EP06789950.0
申请日：2006-08-23
发明人： MCCORMICK, Kevin, D. , BOYCE, Christopher, W. , ASLANIAN, Robert, G. , SHIH, Neng-Yang , FEVRIER, Salem , MANGIARCINA, Pietro , HUANG, Chia-Yu , LIANG, Bo , LIU, Rong-Qiang , LU, Huagang
IPC分类号： C07D401/06 , C07D403/06 , A61K31/435 , A61K31/41 , A61P29/00
CPC分类号： C07D403/02 , C07D401/06 , C07D403/06
摘要： In its many embodiments, the present invention provides imidazole derivatives which are inhibitors of alPha2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition or amelioration of one or more conditions associated with the alpha2C adrenergic receptors using such compounds or pharmaceutical compositions. Formula (I).
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