公开(公告)号：EP3226851B1

公开(公告)日：2020-03-18

申请号：EP15825824.4

申请日：2015-12-07

申请人： Semmelweis University ,  Fujimoto Co. Ltd.

发明人： KNOLL, József ,  MIKLYA, Ildikó ,  FERDINANDY, Péter ,  SCHULER, Dezso ,  SCHAFF, Zsuzsanna ,  ECKHARDT, Sándor

IPC分类号： A61K31/137 ,  A61P35/00

公开(公告)号：EP3226852A1

公开(公告)日：2017-10-11

申请号：EP15825825.1

申请日：2015-12-07

申请人： Semmelweis University ,  Fujimoto Co., Ltd.

发明人： KNOLL, József ,  MIKLYA, Ildikó ,  FERDINANDY, Péter ,  SCHULER, Dezs ,  SCHAFF, Zsuzsanna ,  ECKHARDT, Sándor

IPC分类号： A61K31/137 ,  A61K31/343 ,  A61P35/00

摘要： The invention relates to the field of prevention and treatment of cancer, in particular suppression of tumor manifestation. The invention also relates to compounds for use in this field. A novel tumor manifestation suppression (TMS) regulation in a mammalian brain is recognized. The invention relates to compounds, pharmaceutical preparations, in particular medicaments for use in the prevention and treatment of cancer, in particular suppression of tumor manifestation based on said TMS regulation as well as methods for the same.

公开(公告)号：EP3226852B1

公开(公告)日：2020-03-18

申请号：EP15825825.1

申请日：2015-12-07

申请人： Semmelweis University ,  Fujimoto Co. Ltd.

发明人： KNOLL, József ,  MIKLYA, Ildikó ,  FERDINANDY, Péter ,  SCHULER, Dezso ,  SCHAFF, Zsuzsanna ,  ECKHARDT, Sándor

IPC分类号： A61K31/137 ,  A61K31/343 ,  A61P35/00

公开(公告)号：EP3226851A1

公开(公告)日：2017-10-11

申请号：EP15825824.4

申请日：2015-12-07

申请人： Semmelweis University ,  Fujimoto Co., Ltd.

发明人： KNOLL, József ,  MIKLYA, Ildikó ,  FERDINANDY, Péter ,  SCHULER, Dezso ,  SCHAFF, Zsuzsanna ,  ECKHARDT, Sándor

IPC分类号： A61K31/137 ,  A61P35/00

摘要： The invention relates to the field of prevention and treatment of cancer, in particular suppression of tumor manifestation. The invention also relates to compounds for use in this field. A novel tumor manifestation suppression (TMS) regulation in a mammalian brain is recognized. The invention relates to compounds, pharmaceutical preparations, in particular medicaments for use in the prevention and treatment of cancer, in particular suppression of tumor manifestation based on said TMS regulation as well as methods for the same.

摘要翻译： 本发明涉及癌症预防和治疗领域，特别是抑制肿瘤表现。 本发明还涉及用于该领域的化合物。 认识到哺乳动物脑中的新型肿瘤表现抑制（TMS）调节。 本发明涉及用于预防和治疗癌症的化合物，药物制剂，特别是药物，特别是基于所述TMS调控的肿瘤表现的抑制以及用于其的方法。