公开(公告)号：EP2019142A2

公开(公告)日：2009-01-28

申请号：EP08013335.8

申请日：2005-12-05

申请人： Senesco Technologies, Inc.

发明人： Thompson, John, E. ,  McNamara, Linda

IPC分类号： C12N15/82 ,  C07K14/415

CPC分类号： C12N15/8261 ,  C07K14/415 ,  Y02A40/146

摘要： The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.

摘要翻译： 本发明涉及真核起始因子5A（“eIF-5A”）的独特同种型：衰老诱导的eIF-5A; 创伤/病原体诱导的eIF-5A; 应激eIF-5A和生长eIF-5A，以及编码这三种因子的多核苷酸。 本发明还涉及涉及调节这些因子表达的方法。 本发明还涉及脱氧前苏氨酸合酶（“DHS”），编码DHS的多核苷酸和涉及调节DHS表达的方法。

公开(公告)号：EP2019142A9

公开(公告)日：2009-05-13

申请号：EP08013335.8

申请日：2005-12-05

申请人： Senesco Technologies, Inc.

发明人： Thompson, John, E. ,  McNamara, Linda ,  Wu, Wendy ,  Wang, Tzann-Wei

IPC分类号： C12N15/82 ,  C07K14/415

CPC分类号： C12N15/8261 ,  C07K14/415 ,  Y02A40/146

摘要： The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.

公开(公告)号：EP2019142A3

公开(公告)日：2009-04-01

申请号：EP08013335.8

申请日：2005-12-05

申请人： Senesco Technologies, Inc.

发明人： Thompson, John, E. ,  McNamara, Linda

IPC分类号： C12N15/82 ,  C07K14/415

CPC分类号： C12N15/8261 ,  C07K14/415 ,  Y02A40/146

摘要： The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.