公开(公告)号：EP3626728A1

公开(公告)日：2020-03-25

申请号：EP18845981.2

申请日：2018-06-19

申请人： Seoul National University R & DB Foundation ,  Nibec Co., Ltd.

发明人： HAN, Seung Hyun ,  PARK, Ok-Jin ,  KIM, Jiseon ,  AHN, Ki Bum ,  PARK, Yoon Jeong ,  CHUNG, Chong-Pyoung ,  LEE, Jue-Yeon

IPC分类号： C07K7/08 ,  A23L33/18 ,  A61K38/00

摘要： The present invention relates to a peptide for inhibiting bone resorption and, more specifically, to a peptide for inhibiting bone destruction by inhibiting the differentiation and activity of osteoclasts. According to the present invention, a peptide for inhibiting bone resorption can inhibit bone destruction by inhibiting the differentiation and activity of osteoclasts, and thus can be used as a therapeutic agent for various bone diseases caused by an excessive increase in the activity of osteoclasts.

公开(公告)号：EP3608331A1

公开(公告)日：2020-02-12

申请号：EP18780706.0

申请日：2018-03-19

申请人： Seoul National University R&DB Foundation ,  Nibec Co., Ltd.

发明人： HAN, Seung Hyun ,  KUM, Kee-Yeon ,  AHN, Ki Bum ,  PARK, Ok-Jin ,  CHUNG, Chong-Pyoung ,  PARK, Yoon Jeong ,  LEE, Jue-Yeon

IPC分类号： C07K7/08 ,  A61K8/64 ,  A61Q11/02

摘要： The present invention relates to: a composition for inhibiting biofilms, containing, as an active ingredient, a peptide derived from human β-defensin-3; and a method for inhibiting biofilms by using the composition. The peptide according to the present invention inhibits bacterial biofilms even when used alone and exhibits a remarkably increased biofilm inhibitory effect when used in combination with a conventional dental therapeutic agent, and has an effect of preventing a tooth discoloration side effect caused by a conventional dental therapeutic agent.