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公开(公告)号：EP3288931B1
公开(公告)日：2019-11-06
申请号：EP16785936.2
申请日：2016-04-28
发明人： ZHAO, Xingdong , LI, Tongshuang , TAN, Haohan , CHEN, Zhifang , CHEN, Ling , LIU, Qihong , RONG, Yue , YANG, Lijun , WANG, Xianlong , TAN, Rui , ZHOU, Zuwen , LIU, Bin , LIN, Min , JIANG, Lihua , LIU, Yanxin , LINGHU, Li , SUN, Jing , WANG, Weibo
IPC分类号： C07D401/14 , C07D487/04 , C07D487/10 , C07D471/12 , A61K31/437 , A61K31/4375 , A61P29/00 , A61P35/00
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公开(公告)号：EP3224248A1
公开(公告)日：2017-10-04
申请号：EP15855878.3
申请日：2015-11-01
申请人： Shanghai Fochon Pharmaceutical Co. Ltd , Shanghai Institute Of Materia Medica Chinese Academy of Sciences , Chongqing Fochon Pharmaceutical Co., Ltd.
发明人： ZHAO, Xingdong , LI, Tongshuang , ZHOU, Zuwen , CHEN, Ling , LIU, Qihong , WANG, Xianlong , YANG, Lijun , RONG, Yue , TAN, Rui , YU, Chuiliang , JIANG, Lihua , LIU, Yanxin , LINGHU, Li , SUN, Jing , WANG, Weibo , DING, Jian , MENG, Linghua , GENG, Meiyu
IPC分类号： C07D221/04 , C07D221/00 , C07D513/04 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61P43/00 , A61P35/00
CPC分类号： A61K31/437 , A61K31/4375 , A61K31/505 , A61K31/52 , A61K45/06 , C07D519/00 , A61K2300/00
摘要： Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
摘要翻译： 提供了某些PI3K抑制剂，其药物组合物及其使用方法。
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公开(公告)号：EP3149008A1
公开(公告)日：2017-04-05
申请号：EP15800531.4
申请日：2015-05-27
发明人： WANG, Weibo , ZHAO, Xingdong , LI, Tongshuang , TIAN, Qiang , ZHANG, Huajie , TAN, Haohan , WANG, Xianlong , LIU, Qihong , LI, Zhifu , ZHANG, Weipeng , CHEN, Zhifang , JIANG, Lihua , LIU, Yanxin , LINGHU, Li , LIN, Min , SUN, Jing
IPC分类号： C07D519/00 , A61K31/519 , A61K31/53 , A61P35/00
CPC分类号： C07D519/00 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K45/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D487/04 , C07D491/048 , C07D495/04 , A61K2300/00
摘要： Provided are compound of formula (I) as certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
摘要翻译： 提供作为某些CDK4 / 6抑制剂的式（I）化合物，其药物组合物及其使用方法。
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公开(公告)号：EP3149008B1
公开(公告)日：2018-12-12
申请号：EP15800531.4
申请日：2015-05-27
发明人： WANG, Weibo , ZHAO, Xingdong , LI, Tongshuang , TIAN, Qiang , ZHANG, Huajie , TAN, Haohan , WANG, Xianlong , LIU, Qihong , LI, Zhifu , ZHANG, Weipeng , CHEN, Zhifang , JIANG, Lihua , LIU, Yanxin , LINGHU, Li , LIN, Min , SUN, Jing
IPC分类号： C07D519/00 , A61K31/519 , A61K31/53 , A61P35/00
CPC分类号： C07D519/00 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K45/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D487/04 , C07D491/048 , C07D495/04 , A61K2300/00
摘要： Provided are compound of formula (I) as certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
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公开(公告)号：EP3288931A1
公开(公告)日：2018-03-07
申请号：EP16785936.2
申请日：2016-04-28
发明人： ZHAO, Xingdong , LI, Tongshuang , TAN, Haohan , CHEN, Zhifang , CHEN, Ling , LIU, Qihong , RONG, Yue , YANG, Lijun , WANG, Xianlong , TAN, Rui , ZHOU, Zuwen , LIU, Bin , LIN, Min , JIANG, Lihua , LIU, Yanxin , LINGHU, Li , SUN, Jing , WANG, Weibo
IPC分类号： C07D401/14 , C07D487/04 , C07D487/10 , C07D471/12 , A61K31/437 , A61K31/4375 , A61P29/00 , A61P35/00
摘要： Provided are certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
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6.发明公开
公开(公告)号：EP3976607A1
公开(公告)日：2022-04-06
申请号：EP20814173.9
申请日：2020-06-01
发明人： TAN, Haohan , LIU, Qihong , LIU, Bin , LI, Zhifu , WANG, Xianlong , ZHOU, Zuwen , ZHANG, Weipeng , WANG, Yunling , ZHOU, Chenglin , GAO, Yuwei , JIANG, Lihua , LIU, Yanxin , ZOU, Zongyao , LIN, Shu , YU, Kai , LI, Tongshuang , ZHAO, Xingdong , WANG, Weibo
IPC分类号： C07D417/04 , C07D471/04 , C07D487/04 , A61K31/519 , A61P35/00
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公开(公告)号：EP2986611B1
公开(公告)日：2019-02-06
申请号：EP14785167.9
申请日：2014-04-18
发明人： WANG, Weibo , ZHAO, Xingdong , YUAN, Quan , SHI, Hailong , TIAN, Qiang , LIU, Qihong , ZHOU, Zuwen , WANG, Xianlong , CHEN, Zhifang , CHEN, Ling , TAN, Haohan , FANG, Bo , JIANG, Lihua , LIU, Yanxin , SUN, Jing , ZENG, Fanxin , LI, Tongshuang
IPC分类号： C07D471/04 , A61K31/5025 , A61P35/00
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公开(公告)号：EP3452484A1
公开(公告)日：2019-03-13
申请号：EP17795490.6
申请日：2017-05-05
发明人： ZHAO, Xingdong , LI, Tongshuang , CHEN, Zhifang , TAN, Rui , CHEN, Ling , WANG, Xianlong , YANG, Lijun , ZHOU, Zuwen , LIU, Yanxin , LIN, Min , SUN, Jing , WANG, Weibo
IPC分类号： C07D495/04 , A61K31/519 , A61P35/00
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9.发明公开QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS 审中-公开中华人民共和国，ZUSAMMENSETZUNGEN DAVON UND VERWENDUNG ALS ARZNEIMITTEL
公开(公告)号：EP3022186A1
公开(公告)日：2016-05-25
申请号：EP14825785.0
申请日：2014-07-17
发明人： WANG, Weibo , ZHAO, Xingdong , LI, Tongshuang , TIAN, Qiang , CHEN, Ling , ZHOU, Zuwen , LI, Zhifu , WANG, Xianlong , RONG, Yue , JIANG, Lihua , LIU, Yanxin , SUN, Jing , ZENG, Fanxin
IPC分类号： C07D239/94 , C07D403/12 , A61K31/517 , A61P35/00
CPC分类号： C07D403/12 , A61K31/517 , A61K45/06 , C07D405/14
摘要： Disclosed herein are protein kinase inhibitors, more particularly novel quinazoline derivatives and pharmaceutical compositions thereof, and method of use thereof.
摘要翻译： 本文公开了蛋白激酶抑制剂，更特别的是新的喹唑啉衍生物及其药物组合物及其使用方法。
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公开(公告)号：EP2986611A1
公开(公告)日：2016-02-24
申请号：EP14785167.9
申请日：2014-04-18
发明人： WANG, Weibo , ZHAO, Xingdong , YUAN, Quan , SHI, Hailong , TIAN, Qiang , LIU, Qihong , ZHOU, Zuwen , WANG, Xianlong , CHEN, Zhifang , CHEN, Ling , TAN, Haohan , FANG, Bo , JIANG, Lihua , LIU, Yanxin , SUN, Jing , ZENG, Fanxin , LI, Tongshuang
IPC分类号： C07D487/02 , A61K31/5025 , A61K31/519 , A61P29/00 , A61P35/00
CPC分类号： A61K31/5025 , C07D471/04 , C07D487/04
摘要： Disclosed herein are protein kinase inhibitors, more particularly pyridazine derivatives and pharmaceutical compositions thereof, and method of use thereof.
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