公开(公告)号：EP4011378A1

公开(公告)日：2022-06-15

申请号：EP20849500.2

申请日：2020-08-05

申请人： Shanghai Green Valley Pharmaceutical Co., Ltd. ,  Shanghai Institute Materia Medica, Chinese Academy Of Sciences

发明人： GENG, Meiyu ,  SUN, Guangqiang ,  WANG, Xinyi ,  ZHANG, Jing ,  FENG, Teng

IPC分类号： A61K31/702 ,  A61P3/10 ,  A61P19/02

摘要： A use that relates to mannuronic acid oligosaccharides or a composition comprising same in the treatment of Th1-dominance related diseases. The Th1-dominance related diseases may be selected from Multiple Sclerosis, Crohn's disease, Type I Diabetes, Rheumatoid Arthritis, Hashimoto's thyroiditis, vitiligo, Sjögren's Syndrome, Polycystic ovary syndrome, Celiac Disease and Grave's disease, preferably from Multiple Sclerosis, Crohn's disease and Rheumatoid Arthritis.

公开(公告)号：EP4011395A1

公开(公告)日：2022-06-15

申请号：EP20850878.8

申请日：2020-08-05

申请人： Shanghai Green Valley Pharmaceutical Co., Ltd. ,  Shanghai Institute of Materia Medica, Chinese Academy of Sciences

发明人： GENG, Meiyu ,  SUN, Guangqiang ,  WANG, Xinyi ,  ZHANG, Jing ,  FENG, Teng

IPC分类号： A61K45/00 ,  A61P25/28

摘要： The present invention relates to identification of a carbohydrate drug-sensitive patient in patients having Alzheimer's disease. The present invention provides a method for identifying a carbohydrate drug-sensitive patient in patients having Alzheimer's disease.

公开(公告)号：EP4011394A1

公开(公告)日：2022-06-15

申请号：EP20850618.8

申请日：2020-08-05

申请人： Shanghai Green Valley Pharmaceutical Co., Ltd. ,  Shanghai Institute of Materia Medica, Chinese Academy of Sciences

发明人： GENG, Meiyu ,  SUN, Guangqiang ,  WANG, Xinyi ,  ZHANG, Jing ,  FENG, Teng

IPC分类号： A61K45/00 ,  A61K31/702 ,  G01N33/483 ,  A61P3/10

摘要： Provided is the use of a reagent for inhibiting the uptake of amino acids by naive T cells in the preparation of a drug for treating Alzheimer's disease in a subject.

公开(公告)号：EP4011392A1

公开(公告)日：2022-06-15

申请号：EP20849639.8

申请日：2020-08-05

申请人： Shanghai Green Valley Pharmaceutical Co., Ltd. ,  Shanghai Institute of Materia Medica, Chinese Academy of Sciences

发明人： GENG, Meiyu ,  SUN, Guangqiang ,  WANG, Xinyi ,  ZHANG, Jing ,  FENG, Teng

IPC分类号： A61K45/00 ,  A61P25/28

摘要： The present invention relates to the treatment of Alzheimer's disease. Provided is the use of an reagent for regulating the relative abundance of intestinal microorganisms in the preparation of a medicament for treating Alzheimer's disease in a subjet.

公开(公告)号：EP4011379A1

公开(公告)日：2022-06-15

申请号：EP20850067.8

申请日：2020-08-05

申请人： Shanghai Green Valley Pharmaceutical Co., Ltd. ,  Shanghai Institute of Materia Medica, Chinese Academy of Sciences

发明人： GENG, Meiyu ,  SUN, Guangqiang ,  WANG, Xinyi ,  ZHANG, Jing ,  FENG, Teng

IPC分类号： A61K31/702 ,  G01N33/483 ,  A61P25/28 ,  A61K45/00

摘要： Provided is a use of an agent for regulating an amino acid level in preparing a drug for treating Alzheimer's disease in a subject.