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公开(公告)号:EP3524602A1
公开(公告)日:2019-08-14
申请号:EP17848144.6
申请日:2017-09-06
申请人: Shanghai Haihe Pharmaceutical Co., Ltd. , Shanghai Institute of Materia Medica, Chinese Academy of Sciences
发明人: CHEN, Xuxing , GENG, Meiyu , JIANG, Lei , CHEN, Yi , CAO, Jianhua , JIANG, Qingyun , SHEN, Qianqian , DING, Jian , YAO, Yucai , ZHAO, Zhao , XIONG, Yuanfang
IPC分类号: C07D471/04 , C07D519/00 , C07D471/14 , C07D491/147 , A61K31/444 , A61K31/496 , A61K31/5377 , A61K31/4545 , A61P35/00 , A61P37/06 , A61K31/437
摘要: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.