公开(公告)号：EP4354487A1

公开(公告)日：2024-04-17

申请号：EP21945082.2

申请日：2021-06-09

申请人： Shimadzu Corporation

发明人： MIYAZAKI, Yuta ,  OSHIRO, Tomoyuki

IPC分类号： H01J49/00 ,  H01J49/40

CPC分类号： H01J49/40 ,  H01J49/00

摘要： A mode of TOFMS according to the present invention includes flight space formation electrodes (11, 12) configured to form a flight space for separating ions derived from a component contained in a sample according to a m/z, an ion detection unit (13) configured to detect ions that have flown in the flight space, voltage switching units (4, 2) configured to switch a voltage to be applied to the flight space formation electrode from a first voltage for flying ions of a first polarity to a second voltage for flying ions of a second polarity at a given switching timing, ion information acquisition units (30, 32) configured to obtain a time of flight during which the ions fly in the flight space or a m/z of the ions based on a detection result of the ions of the second polarity obtained by the ion detection unit after the voltage has been switched by the voltage switching unit, a correction information storage unit (31) configured to store correction information related to a deviation in time of flight or a m/z associated with an elapsed time from the switching timing, and a correction unit (33) configured to correct the flight time or the m/z obtained by the ion information acquisition unit according to an elapsed time from the switching timing when the detection result of the ion is obtained using the correction information stored in the correction information storage unit.

公开(公告)号：EP3404696A1

公开(公告)日：2018-11-21

申请号：EP16884942.0

申请日：2016-01-15

申请人： Shimadzu Corporation

发明人： FURUHASHI, Osamu ,  OKUMURA, Daisuke ,  OSHIRO, Tomoyuki

IPC分类号： H01J49/40 ,  G01N27/62

CPC分类号： G01N27/62 ,  H01J49/401

摘要： A multipole ion guide (30) including a plurality of rod electrodes arranged at an angle to the central axis (C) is placed within a collision cell (13) located in the previous stage of an orthogonal accelerator (16). Radio-frequency voltages with opposite phases are applied to the rod electrodes of the ion guide (30) so that any two rod electrodes neighboring each other in the circumferential direction have opposite phases of the voltage. A depth gradient of the pseudopotential is thereby formed from the entrance end toward the exit end within the space surrounded by the rod electrodes, and ions are accelerated by this gradient. During an ion-accumulating process, a direct voltage having the same polarity as the ions is applied to the exit lens electrode (132) to form a potential barrier for accumulating ions. Among the ions repelled by the potential barrier, ions having smaller m/z return closer to the entrance end. Therefore, when the potential barrier is removed and ions are discharged, ions having smaller m/z are discharged at later points in time than those having larger m/z. Therefore, a wide m/z range of ions can be simultaneously accelerated and ejected by an orthogonal accelerator (16).

公开(公告)号：EP3367422A1

公开(公告)日：2018-08-29

申请号：EP15906735.4

申请日：2015-10-23

申请人： Shimadzu Corporation

发明人： OSHIRO, Tomoyuki

IPC分类号： H01J49/40

CPC分类号： H01J49/401 ,  H01J49/0009 ,  H01J49/08

摘要： Provided is an orthogonal acceleration time-of-flight mass spectrometer in which an ion injected into an orthogonal acceleration area is accelerated in a direction orthogonal to a direction of the injection and thereby ejected into a flight space, and a mass-to-charge ratio of the ion is determined based on a time of flight of the ion. The mass spectrometer includes: an ion transport electrode (241) for transporting an ion into the orthogonal acceleration area; an orthogonal acceleration electrode (242) for orthogonally accelerating an ion injected into the orthogonal acceleration area; a flight-path-defining electrode (246) including a flight tube; a storage section (41) in which applied-voltage information which is a set of information concerning levels of voltages applied to the orthogonal acceleration electrode (241), the ion transport electrode, and the flight-path-defining electrode is stored, where an applied voltage whose level changes depending on an ion-ejection period is related to at least one of the electrodes; and a voltage supplier (44) for applying voltages to the aforementioned one of the electrodes.