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1.发明授权Use of acyl L-carnitine gamma-hydroxybutyrate for the manufacture of a medicamentfor the treatment of drug addiction 失效凡使用酰基-L-肉毒碱伽马羟基丁酸酯用于制备药物的用途药物依赖的治疗
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2.发明公开Use of acyl L-carnitine gamma-hydroxybutyrate for the treatment of alcoholism 失效Verwendung von Ester von Acyl-L-Carnitin mitGammahydroxybuttersäurezur Behandlung von Alkoholismus。
公开(公告)号：EP0616805A1
公开(公告)日：1994-09-28
申请号：EP94830122.1
申请日：1994-03-21
IPC分类号： A61K31/22 , A61K31/205
CPC分类号： A61K31/22 , A61K31/205
摘要： The use of acyl L-carnitine esters with gamma-hydroxybutyric acid is described of the formula
wherein R is straight or branched acyl with from 2 to 5 carbon atoms, preferably acetyl, propionyl, n-butyryl, isobutyryl and isovaleryl, and X is the anion of a pharmacologically acceptable acid or of the corresponding inner salts to produce a drug to suppress withdrawal symptoms and craving for alcohol in alcoholics.摘要翻译： 酰基L-肉碱酯与γ-羟基丁酸的用途描述于式CHEM，其中R是具有2至5个碳原子的直链或支链酰基，优选乙酰基，丙酰基，正丁酰基，异丁酰基和异戊酰基，以及 X是药理学上可接受的酸或相应的内盐的阴离子，以产生抑制戒酒症状和酗酒中酒精的药物。
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3.发明授权Use of acyl L-carnitine gamma-hydroxybutyrate for the treatment of alcoholism 失效使用与Gammahydroxybuttersäure酰基L-肉毒碱的酯用于治疗酒精中毒
公开(公告)号：EP0616805B1
公开(公告)日：1998-06-10
申请号：EP94830122.1
申请日：1994-03-21
IPC分类号： A61K31/22 , A61K31/205
CPC分类号： A61K31/22 , A61K31/205
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4.发明公开Use of acyl L-carnitine gamma-hydroxybutyrate for the treatment of drug addiction 失效Verwendung van Acyl-L-Carnitin-gamma-hydroxybutyraten zur Behandlung derDrogenabhängigkeit。
公开(公告)号：EP0630648A1
公开(公告)日：1994-12-28
申请号：EP94830299.7
申请日：1994-06-20
IPC分类号： A61K31/22
CPC分类号： A61K31/22
摘要： The use of acyl L-carnitine esters with gamma-hydroxybutyric acid is described in which the acyl is preferably acetyl, propionyl, n-butyryl, isobutyryl, valeryl or isovaleryl to produce a drug to suppress withdrawal symptoms and the craving for self-administration of narcotic substances in drug addicts.
摘要翻译： 描述了使用酰基L-肉碱酯与γ-羟基丁酸，其中酰基优选为乙酰基，丙酰基，正丁酰基，异丁酰基，戊酰基或异戊酰基，以产生抑制戒断症状的药物和自身给药的渴望 吸毒成瘾者的麻醉药物。
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