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1.发明授权HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 有权杂THEREOF组合物和治疗方法，这些方法
公开(公告)号：EP2078016B1
公开(公告)日：2012-02-01
申请号：EP07861467.4
申请日：2007-10-18
发明人： MORTENSEN, Deborah Sue , MEDEROS, Maria Mercedes Delgado , SAPIENZA, John Joseph , ALBERS, Ronald J. , LEE, Branden G. , HARRIS, Roy Leonard., III , SHEVLIN, Graziella Isabel , HUANG, Dehua , SCHWARZ, Kimberly Lyn , PACKARD, Garrick K. , PARNES, Jason Simon , PAPA, Patrick William , TEHRANI, Lida Radnia , PERRIN-NINKOVIC, Sophie , RIGGS, Jennifer R
IPC分类号： C07D471/04 , C07D487/04 , C07D498/04 , A61P35/00
CPC分类号： C07D471/04 , C07D487/04 , C07D498/04
摘要： Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
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2.发明公开HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 有权杂THEREOF组合物和治疗方法，这些方法
公开(公告)号：EP2078016A2
公开(公告)日：2009-07-15
申请号：EP07861467.4
申请日：2007-10-18
发明人： MORTENSEN, Deborah Sue , MEDEROS, Maria Mercedes Delgado , SAPIENZA, John Joseph , ALBERS, Ronald J. , LEE, Branden G. , HARRIS, Roy Leonard., III , SHEVLIN, Graziella Isabel , HUANG, Dehua , SCHWARZ, Kimberly Lyn , PACKARD, Garrick K. , PARNES, Jason Simon , PAPA, Patrick William , TEHRANI, Lida Radnia , PERRIN-NINKOVIC, Sophie
IPC分类号： C07D471/04 , C07D487/04 , C07D498/04 , A61P35/00
CPC分类号： C07D471/04 , C07D487/04 , C07D498/04
摘要： Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
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3.发明授权HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS 有权杂THEREOF组合物及其作为蛋白激酶抑制剂
公开(公告)号：EP2078018B1
公开(公告)日：2012-03-14
申请号：EP07861468.2
申请日：2007-10-18
发明人： MORTENSEN, Deborah Sue , MEDEROS, Maria Mercedes Delgado , SAPIENZA, John Joseph , ALBERS, Ronald J. , LEE, Branden G. , HUANG, Dehua , SCHWARZ, Kimberly Lyn , PARNES, Jason Simon , RIGGS, Jennifer R. , PAPA, Patrick William
IPC分类号： C07D473/00 , C07D475/00 , A61K31/519 , A61K31/522 , A61P29/00 , A61P35/00
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
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4.发明公开HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS 有权杂THEREOF组合物及其作为蛋白激酶抑制剂
公开(公告)号：EP2078018A1
公开(公告)日：2009-07-15
申请号：EP07861468.2
申请日：2007-10-18
发明人： MORTENSEN, Deborah Sue , MEDEROS, Maria Mercedes Delgado , SAPIENZA, John Joseph , ALBERS, Ronald J. , LEE, Branden G. , HUANG, Dehua , SCHWARZ, Kimberly Lyn , PARNES, Jason Simon , RIGGS, Jennifer R. , PAPA, Patrick William
IPC分类号： C07D473/00 , C07D475/00 , A61K31/519 , A61K31/522 , A61P29/00 , A61P35/00
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
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