专利检索 ap:("Sirna Therapeutics, Inc.") AND inv:"WANG, Lijun" 第 1 页

1.

发明授权
TETRAGALNAC CONTAINING CONJUGATES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES 有权

公开(公告)号：EP2844663B1

公开(公告)日：2020-03-25

申请号：EP13784779.4

申请日：2013-05-01

申请人： Sirna Therapeutics, Inc.

发明人： TELLERS, David , COLLETTI, Steven, L. , DUDKIN, Vadim , IKEMOTO, Norihiro , LIAO, Hongbiao , PARISH, Craig , PEI, Tao , SHAW, Anthony , TRUONG, Quang , WANG, Lijun , YUAN, Yu , ZHU, Man

IPC分类号： C07H15/26 , C12N15/113 , A61K47/54

2.

发明公开
NOVEL TETRAGALNAC CONTAINING CONJUGATES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES 审中-公开
标题翻译：新型TETRAGALNAC含缀合物和方法释放的寡核苷酸

公开(公告)号：EP2844663A1

公开(公告)日：2015-03-11

申请号：EP13784779.4

申请日：2013-05-01

申请人： Sirna Therapeutics, Inc.

发明人： TELLERS, David , COLLETTI, Steven, L. , DUDKIN, Vadim , IKEMOTO, Norihiro , LIAO, Hongbiao , PARISH, Craig , PEI, Tao , SHAW, Anthony , TRUONG, Quang , WANG, Lijun , YUAN, Yu , ZHU, Man

IPC分类号： C07H19/056

CPC分类号： C12N15/113 , A61K47/549 , C07H15/26 , C12N2310/11 , C12N2310/14 , C12N2310/351

摘要： Disclosed herein is a modular composition comprising 1) an oligonucleotide; 2) one or more tetraGalNAc ligands of Formula (I), which may be the same or different; optionally, 3) one or more linkers, which may be the same or different; and optionally, 4) one or more targeting ligands, solubilizing agents, pharmacokinetics enhancing agents, lipids, and/or masking agents.