DESIGN-PRINZIP FÜR DIE KONSTRUKTION VON EXPRESSIONSKONSTRUKTEN FÜR DIE GENTHERAPIE
    1.
    发明公开
    DESIGN-PRINZIP FÜR DIE KONSTRUKTION VON EXPRESSIONSKONSTRUKTEN FÜR DIE GENTHERAPIE 失效
    为了表述施工图设计原理构建的基因治疗

    公开(公告)号:EP0941318A1

    公开(公告)日:1999-09-15

    申请号:EP97949949.0

    申请日:1997-11-13

    申请人: Soft Gene GmbH

    IPC分类号: A61K48 C12N15

    摘要: The invention concerns an expressible nucleic acid construct which contains only the sequence information necessary for expressing a gene for RNA or protein synthesis. Expression constructs of this type can be used in gene therapy and genetic vaccination and avoid many of the risks associated with constructs today. The invention further concerns the possibility of improving the conveying of the construct into cells or tissue by covalent linkage of the construct, for example to particles or peptides.

    HANTELFÖRMIGE EXPRESSIONSKONSTRUKTE FÜR DIE GENTHERAPIE
    2.
    发明授权
    HANTELFÖRMIGE EXPRESSIONSKONSTRUKTE FÜR DIE GENTHERAPIE 失效
    WEIGHT形表达构建基因治疗

    公开(公告)号:EP0941318B1

    公开(公告)日:2001-01-17

    申请号:EP97949949.8

    申请日:1997-11-13

    申请人: Soft Gene GmbH

    IPC分类号: C12N15/11 C12N15/89 A61K48/00

    摘要: The invention concerns an expressible nucleic acid construct which contains only the sequence information necessary for expressing a gene for RNA or protein synthesis. Expression constructs of this type can be used in gene therapy and genetic vaccination and avoid many of the risks associated with constructs today. The invention further concerns the possibility of improving the conveying of the construct into cells or tissue by covalent linkage of the construct, for example to particles or peptides.

    HANTELFÖRMIGE EXPRESSIONSKONSTRUKTE FÜR DIE GENTHERAPIE
    3.
    发明授权
    HANTELFÖRMIGE EXPRESSIONSKONSTRUKTE FÜR DIE GENTHERAPIE 失效
    HANTELFÖRMIGEEXPRESSIONSKONSTRUKTEFÜRDIE GENTHERAPIE

    公开(公告)号:EP0941318B9

    公开(公告)日:2001-12-19

    申请号:EP97949949.8

    申请日:1997-11-13

    申请人: Soft Gene GmbH

    IPC分类号: C12N15/11 C12N15/89 A61K48/00

    摘要: The invention concerns an expressible nucleic acid construct which contains only the sequence information necessary for expressing a gene for RNA or protein synthesis. Expression constructs of this type can be used in gene therapy and genetic vaccination and avoid many of the risks associated with constructs today. The invention further concerns the possibility of improving the conveying of the construct into cells or tissue by covalent linkage of the construct, for example to particles or peptides.

    摘要翻译: 本发明涉及可表达的核酸构建体,其仅含有表达RNA或蛋白质合成基因所必需的序列信息。 这种表达构建体可用于基因治疗和基因疫苗接种,并避免今天与构建体相关的许多风险。 本发明进一步涉及通过构建体例如颗粒或肽的共价连接改善构建体向细胞或组织的输送的可能性。