公开(公告)号：EP1191030B1

公开(公告)日：2005-05-04

申请号：EP01122364.1

申请日：2001-09-19

申请人： Solvias AG

发明人： Pfaltz, Andreas ,  Blankenstein, Joerg R. ,  Menges, Frederik

IPC分类号： C07F9/653 ,  C07D263/16 ,  C07D263/14 ,  C07F15/00 ,  C07B53/00 ,  C07C233/18

CPC分类号： C07D263/16 ,  C07B53/00 ,  C07C233/18 ,  C07D263/14 ,  C07F9/653 ,  C07F15/0033

公开(公告)号：EP1191030A3

公开(公告)日：2002-07-17

申请号：EP01122364.1

申请日：2001-09-19

申请人： Solvias AG

发明人： Pfaltz, Andreas ,  Blankenstein, Joerg R. ,  Menges, Frederik

IPC分类号： C07F9/653 ,  C07D263/16 ,  C07D263/14 ,  C07F15/00 ,  C07B53/00 ,  C07C233/18

CPC分类号： C07D263/16 ,  C07B53/00 ,  C07C233/18 ,  C07D263/14 ,  C07F9/653 ,  C07F15/0033

摘要： Compounds of formulae I and Ia, wherein X 1 is secondary phosphino; R 3 is hydrogen, a hydrocarbon radical having from 1 to 20 carbon atoms, a heterohydrocarbon radical, bonded via a carbon atom, having from 2 to 20 atoms and at least one hetero atom selected from the group O, S and NR, or ferrocenyl; R is H or C 1 -C 4 alkyl; each R 4 individually or both R 4 together are a hydrocarbon radical having from 1 to 20 carbon atoms; and R 01 and R 02 are each independently of the other a hydrogen atom or a hydrocarbon radical having from 1 to 20 carbon atoms, are chiral ligands for metal complexes with metals of sub-groups I and VIII, which are catalysts for asymmetric addition reactions, for example of hydrogen, to prochiral unsaturated organic compounds.

公开(公告)号：EP1191030A2

公开(公告)日：2002-03-27

申请号：EP01122364.1

申请日：2001-09-19

申请人： Solvias AG

发明人： Pfaltz, Andreas ,  Blankenstein, Joerg R. ,  Menges, Frederik

IPC分类号： C07F9/653 ,  C07D263/16 ,  C07D263/14 ,  C07F15/00 ,  C07B53/00 ,  C07C233/18

CPC分类号： C07D263/16 ,  C07B53/00 ,  C07C233/18 ,  C07D263/14 ,  C07F9/653 ,  C07F15/0033

摘要： Compounds of formulae I and Ia,
wherein
X 1 is secondary phosphino; R 3 is hydrogen, a hydrocarbon radical having from 1 to 20 carbon atoms, a heterohydrocarbon radical, bonded via a carbon atom, having from 2 to 20 atoms and at least one hetero atom selected from the group O, S and NR, or ferrocenyl; R is H or C 1 -C 4 alkyl; each R 4 individually or both R 4 together are a hydrocarbon radical having from 1 to 20 carbon atoms; and R 01 and R 02 are each independently of the other a hydrogen atom or a hydrocarbon radical having from 1 to 20 carbon atoms, are chiral ligands for metal complexes with metals of sub-groups I and VIII, which are catalysts for asymmetric addition reactions, for example of hydrogen, to prochiral unsaturated organic compounds.

摘要翻译： 式I和Ia化合物，其中X 1为仲膦基; R3是氢，具有1-20个碳原子的烃基，通过碳原子键合的杂烃基，具有2至20个原子和至少一个选自O，S和NR的杂原子或二茂铁基; R是H或C 1 -C 4烷基; 每个R 4单独或两个R 4一起是具有1至20个碳原子的烃基; 和R 01和R 02各自独立地为氢原子或具有1至20个碳原子的烃基，是与作为不对称加成反应的催化剂的分组I和VIII的金属的金属络合物的手性配体，用于 氢的例子，涉及前手性不饱和有机化合物。