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公开(公告)号：EP2859121B1
公开(公告)日：2016-11-30
申请号：EP13801106.9
申请日：2013-06-07
申请人： Somalogic, Inc.
IPC分类号： C12Q1/68 , C07H21/00 , G01N33/543
CPC分类号： G01N33/5308 , C07H21/00 , C12Q1/6804 , C12Q1/6811 , C12Q1/6837 , G01N33/543 , G01N33/54306 , G01N33/54393 , G01N33/68 , G01N33/6803 , G01N2570/00 , C12Q2525/113 , C12Q2525/205 , C12Q2561/101
摘要： The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic acid target (e.g., a protein target) in a test sample by detecting and quantifying a nucleic acid (i.e., an aptamer) where the aptamer-aptamer interactions are significantly reduced or eliminated while maintaining the aptamer-target interaction.
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2.发明公开SELECTION OF PREFERRED SAMPLE HANDLING AND PROCESSING PROTOCOL FOR IDENTIFICATION OF DISEASE BIOMARKERS AND SAMPLE QUALITY ASSESSMENT 审中-公开优选的样品处理加工与PROTOCOL用于识别KRANKHEITSBIOMARKERN和样品质量评定SELECTION
公开(公告)号：EP2771451A1
公开(公告)日：2014-09-03
申请号：EP12843012.1
申请日：2012-10-24
申请人： Somalogic, Inc.
发明人： RIEL-MEHAN, Michael , STEWART, Alex A.E. , SANDERS, Glenn , OSTROFF, Rachel M. , WILLIAMS, Stephen Alaric , BRODY, Edward N.
IPC分类号： C12M1/34
摘要： The subject invention relates to methods for obtaining biological samples of improved quality. It encompasses the identification of markers or proteins in biological samples that are altered due to variations in sample collection, handling and processing. They are also useful for correcting variations in measured results for disease biomarkers. Further, they can permit the rejection of samples or groups of samples as necessary if it is determined that their collection method was not in accordance with the predetermined protocol. Other advantages useful to the skilled artisan are described herein.
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公开(公告)号：EP2859121A1
公开(公告)日：2015-04-15
申请号：EP13801106.9
申请日：2013-06-07
申请人： Somalogic, Inc.
IPC分类号： C12Q1/68 , C07H21/00 , G01N33/543
CPC分类号： G01N33/5308 , C07H21/00 , C12Q1/6804 , C12Q1/6811 , C12Q1/6837 , G01N33/543 , G01N33/54306 , G01N33/54393 , G01N33/68 , G01N33/6803 , G01N2570/00 , C12Q2525/113 , C12Q2525/205 , C12Q2561/101
摘要： The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic acid target (e.g., a protein target) in a test sample by detecting and quantifying a nucleic acid (i.e., an aptamer) where the aptamer-aptamer interactions are significantly reduced or eliminated while maintaining the aptamer-target interaction.
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