SAMPLE ISOLATION KIT, SAMPLE ISOLATION DEVICE

    公开(公告)号:EP3838407A1

    公开(公告)日:2021-06-23

    申请号:EP20211510.1

    申请日:2017-03-10

    申请人: Sony Corporation

    IPC分类号: B01L3/00 G01N15/14 G01N15/10

    摘要: According to some aspects, a sample isolation kit is provided. The sample isolation kit includes a housing configured to detachably couple to a sample fluid channel of a microchip and provide a sample to the microchip. The housing and the microchip are coupled using a hermetic seal. The sample isolation kit further includes a storage housing configured to detachably couple to an isolation channel of the microchip and receive a target biological sample isolated from the sample by the microchip. The storage housing and the microchip are coupled using a hermetic seal.

    MICROCHIP FOR SEPARATING MICROPARTICLES, AND DEVICE FOR SEPARATING MICROPARTICLES

    公开(公告)号:EP3712593A1

    公开(公告)日:2020-09-23

    申请号:EP18878098.5

    申请日:2018-11-09

    申请人: Sony Corporation

    摘要: A microparticle sorting microchip for a flow cytometer is provided to enable sorting of microparticles at higher speed, higher purity, and higher acquisition rate. The microparticle sorting microchip includes a main channel through which a microparticle-containing fluid flows, a trap channel coaxially communicating with the main channel, a trap chamber communicating with the trap channel, and a gate channel intersecting the trap channel. The trap channel has an opening intersecting the gate channel. The trap channel has a smaller cross-sectional area upstream of the opening than downstream of the opening along a direction in which the microparticle-containing fluid flows.

    METHOD FOR ANALYZING CELL, CHIP FOR CELL ANALYSIS, REAGENT FOR CELL ANALYSIS, KIT FOR CELL ANALYSIS, AND APPARATUS FOR CELL ANALYSIS

    公开(公告)号:EP3362795A1

    公开(公告)日:2018-08-22

    申请号:EP16756813.8

    申请日:2016-08-04

    申请人: Sony Corporation

    IPC分类号: G01N33/569

    摘要: According to some aspects, a method for analyzing a cell is provided. The method includes trapping the cell by binding a first molecule to the cell. The method further includes binding a second molecule to the cell. The second molecule includes a binding portion capable of specific binding to a cell-surface molecule of the cell. The second molecule further includes an identifying portion, a labeling portion coupled to the identifying portion, and a stimulus-degradable linker between the binding portion and the identification portion. The method further includes detaching the identifying portion from the binding portion by stimulating the stimulus-degradable linker where the detached identifying portion is coupled to the labeling portion. The method further includes binding the detached identifying portion through specific binding to an identifying portion recognizing molecule and detecting the labeling portion.