公开(公告)号：EP3193843A1

公开(公告)日：2017-07-26

申请号：EP15720404.1

申请日：2015-03-26

Applicant: Steerlife India Private Limited

Inventor： PADMANABHAN, Babu ,  SHETTY, Rakshit ,  KULKARNI, Vijay ,  SEN, Himadri ,  BHUSHAN, Indu

IPC: A61K9/46 ,  A61K9/16 ,  A61K31/385 ,  A61K31/546 ,  A61K31/60

CPC classification number: A61K9/0007 ,  A61K9/0053 ,  A61K9/1611 ,  A61K9/1617 ,  A61K9/1682 ,  A61K9/1694 ,  A61K9/2009 ,  A61K9/2013 ,  A61K31/198 ,  A61K31/546 ,  A61K31/616 ,  A61K45/06 ,  A61K2300/00

Abstract: The present disclosure concerns effervescent compositions and methods of making and using the same. In some embodiments, the disclosed effervescent compositions are formed from an input blend comprising an acid and a base by granulating the input blend in a twin-screw processor. The granules formed from the input blend can be formed by an
in situ granulating agent, which can be a portion of the acid that melts during granulation. In some embodiments, the effervescent compositions can be made using a twin-screw processor comprising an intake zone for receiving an input blend comprising an acid and a base; a granulation initiation zone for melting only a portion of the acid to serve as an
in situ granulating agent; a granulation completion zone for granulating the input blend; and an outlet for discharging the granules.

Abstract translation: 本公开涉及泡腾组合物及其制备和使用方法。 在一些实施方案中，公开的泡腾组合物由包含酸和碱的输入混合物通过在双螺杆处理器中将输入混合物制粒而形成。 由输入共混物形成的颗粒可以通过原位制粒剂形成，该制粒剂可以是在制粒过程中熔化的一部分酸。 在一些实施方案中，泡腾组合物可以使用双螺杆加工器制造，所述双螺杆加工器包括用于接收包含酸和碱的输入混合物的吸入区; 用于仅熔化一部分酸以用作原位制粒剂的造粒起始区; 用于粒化输入混合物的粒化完成区; 和用于排出颗粒的出口。

公开(公告)号：EP3003682B1

公开(公告)日：2019-11-20

申请号：EP14803934.0

申请日：2014-05-27

Applicant: Steerlife India Private Limited

Inventor： PADMANABHAN, Bahu ,  PRODDUTURI, Suneela ,  SEN, Himadri

IPC: B29C48/405 ,  B29C48/67 ,  B29C48/59 ,  B29C48/82 ,  A61K9/16 ,  B29K91/00 ,  B29C48/40 ,  B29C48/00 ,  B29C48/85

公开(公告)号：EP3359156A2

公开(公告)日：2018-08-15

申请号：EP16853180.4

申请日：2016-10-07

Applicant: Steerlife India Private Limited

Inventor： PADMANABHAN, Babu ,  SEN, Himadri ,  BHUSHAN, Indu ,  KULKARNI, Vijay ,  SHETTY, Rakshith ,  GURRAM, Aravind Kumar

IPC: A61K31/4985 ,  A61K31/40 ,  A61K31/506 ,  A61K9/20

CPC classification number: A61K31/522 ,  A61K9/0007 ,  A61K9/2018 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4985 ,  A61K31/515

Abstract: A rapidly disintegrating tablet comprising a therapeutically effective amount of a DPP- IV inhibitor and an acid-base couple having mineral content below the daily intake limits is disclosed. The rapidly disintegrating tablet has a sodium content less than 10 mg and a potassium content less than 15 mg. A process for preparation of the rapidly disintegrating tablet comprising the DPP-IV inhibitor is also disclosed.

公开(公告)号：EP3328603A1

公开(公告)日：2018-06-06

申请号：EP16832396.2

申请日：2016-08-01

Applicant: Steerlife India Private Limited

Inventor： GHIKE, Radhika ,  KULKARNI, Vijay ,  BHUSHAN, Indu ,  SEN, Himadri ,  PADMANABHAN, Babu ,  RAO, Vinay

IPC: B29B7/48 ,  B29B7/50 ,  B29C47/40

CPC classification number: B01J2/20 ,  A61J3/02 ,  A61K9/1652 ,  A61K9/1694 ,  B01J2/28 ,  B01J2/30 ,  B29B9/06 ,  B29C47/0011 ,  B29C47/40 ,  B29C47/6056 ,  B29C47/6075 ,  B29C47/92 ,  B29C2947/926 ,  B29C2947/92723

Abstract: The present disclosure relates to a process for preparing granules from an input material or a powder material. The process comprises feeding the input material for granulation in the processor using one or more powder feeders, introducing steam as a granulation activating agent in the processor, granulating the input material in presence of the steam to form granules, and optionally collecting the granules from a discharge zone of the processor, wherein feed rate of the steam into the processor is determined based on feed rate of the input material into the processor. A co-rotating twin-screw processor for preparing granules is also discl