公开(公告)号：EP3636630A1

公开(公告)日：2020-04-15

申请号：EP18798982.7

申请日：2018-05-02

申请人： Sumitomo Chemical Company Limited

发明人： KAWAMURA, Mitsunobu ,  OKAMOTO, Hiroaki

IPC分类号： C07C227/16 ,  C07C229/48

摘要： 1-Aminocyclopropanecarboxylic acid non-hydrate can be obtained by
treating 1-aminocyclopropanecarboxylic acid hydrochloride with a tertiary amine in the presence of a C 3 -C 4 alcohol and water, keeping the reaction mixture at 50°C or below,
collecting the precipitated crystal of 1-aminocyclopropanecarboxylic acid 0.5 hydrate by filtration, and heating the obtained crystal to 80 to 245°C.

公开(公告)号：EP3623360A1

公开(公告)日：2020-03-18

申请号：EP18798285.5

申请日：2018-05-02

申请人： Sumitomo Chemical Company, Limited

发明人： KAWAMURA, Mitsunobu ,  OKAMOTO, Hiroaki ,  TAKEBAYASHI, Kosuke

IPC分类号： C07C227/16 ,  C07C227/40 ,  C07C229/48

摘要： 1-Aminocyclopropanecarboxylic acid non-hydrate can be obtained by
treating 1-aminocyclopropanecarboxylic acid hydrochloride with a tertiary amine in the presence of a C 3 -C 4 alcohol and water, keeping the reaction mixture at 50°C or below,
collecting the precipitated crystal of 1-aminocyclopropanecarboxylic acid 0.5 hydrate by filtration, and contacting the obtained crystal with a C 1 -C 2 alcohol.

公开(公告)号：EP2725005B1

公开(公告)日：2017-08-02

申请号：EP12804734.7

申请日：2012-06-27

申请人： Sumitomo Chemical Company Limited

发明人： KAWAMURA, Mitsunobu ,  TAKIMOTO, Masashi ,  YAMAOKA, Tomonori ,  ONOGAWA, Yoshio

IPC分类号： C07C45/64 ,  C07C45/43 ,  C07C47/575 ,  C07B61/00 ,  C07C47/55

CPC分类号： C07C45/64 ,  C07C45/43 ,  C07C47/575 ,  C07C47/55

公开(公告)号：EP2725005A1

公开(公告)日：2014-04-30

申请号：EP12804734.7

申请日：2012-06-27

申请人： Sumitomo Chemical Company Limited

发明人： KAWAMURA, Mitsunobu ,  TAKIMOTO, Masashi ,  YAMAOKA, Tomonori ,  ONOGAWA, Yoshio

IPC分类号： C07C45/64 ,  C07C45/43 ,  C07C47/575 ,  C07B61/00

CPC分类号： C07C45/64 ,  C07C45/43 ,  C07C47/575 ,  C07C47/55

摘要： A new process for producing a 2-(aryloxymethyl)benzaldehyde compound and the like are provided. More particularly, a process for producing a 2-(aryloxymethyl)benzaldehyde compound represented by formula (4) comprising step (A) of hydrolyzing a compound represented by the following formula (1); and step (B) of reacting a compound represented by formula (2) obtained in step (A) and a compound represented by formula (3) or a salt thereof is provided;


Ar-OH (3)

in formulae, X 1 , X 2 and X 3 each represent independently a chlorine atom, a bromine atom or an iodine atom, Q 1 , Q 2 , Q 3 and Q 4 each represent independently a hydrogen atom or a halogen atom, and Ar represents a phenyl group optionally having a substituent).

摘要翻译： 提供了一种新的2-（芳氧基甲基）苯甲醛化合物的制备方法。 更具体地说，涉及制备由式（4）表示的2-（芳氧基甲基）苯甲醛化合物的方法，包括水解由下式（1）表示的化合物的步骤（A）; 并且提供使步骤（A）中获得的式（2）表示的化合物与由式（3）表示的化合物或其盐反应的步骤（B） 式中的Ar-OH（3）X 1，X 2和X 3各自独立地表示氯原子，溴原子或碘原子，Q 1，Q 2，Q 3和Q 4各自独立地表示氢原子或 卤素原子，Ar表示任选具有取代基的苯基）。