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公开(公告)号：EP1738751A2
公开(公告)日：2007-01-03
申请号：EP06019650.8
申请日：2002-01-11
发明人： Shanghvi, Dilip Shantilal Sun Pharmaceutical , Ganorkar, Kirti Wardhaman Sun Pharmaceutical , Zala, Yashoraj Rupsinh. Sun Pharmaceutical Adv. R. , Dharmadhikari, Nitin B. Sun Pharmaceutical Adv. R. , Khanna, Satish C.
CPC分类号： A61K9/4808 , A61K9/1623 , A61K9/1652 , A61K9/2054 , A61K9/5047 , A61K9/5084 , A61K31/155 , A61K31/64 , A61K45/06 , A61K2300/00
摘要： The present invention provides to a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system, wherein the time of release of the two or more therapeutically active agents is designed to provide desired control on the disease condition. The present invention also provides a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system at a specified time prior to food intake by the patient. The present invention further provides a spaced drug delivery system that releases two or more antidiabetic agents at different times after oral administration, for the treatment of diabetes mellitus or conditions associated with diabetes mellitus. More particularly, the present invention provides a spaced drug delivery system that immediately releases one or more antidiabetic agents after oral administration of the system, and releases as a pulse one or more antidiabetic agents in a reliable manner at about a predetermined time after oral administration of the system.
摘要翻译： 本发明提供了给予两种或更多种治疗活性剂的方法，其包括对患者口服施用间隔的药物递送系统，其中两种或更多种治疗活性剂的释放时间被设计为提供对疾病的期望控制 条件。 本发明还提供了一种给予两种或多种治疗活性剂的方法，包括在患者食物摄入之前的特定时间向患者口服给予间隔的药物递送系统。 本发明还提供间隔药物递送系统，其在口服给药后的不同时间释放两种或更多种抗糖尿病药，用于治疗糖尿病或与糖尿病相关的病症。 更具体地说，本发明提供了一种间隔药物递送系统，其在口服给予系统后立即释放一种或多种抗糖尿病药，并且在口服给药后大约预定时间以可靠方式作为脉冲释放一种或多种抗糖尿病药 系统。
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公开(公告)号：EP1738751A3
公开(公告)日：2007-01-17
申请号：EP06019650.8
申请日：2002-01-11
发明人： Shanghvi, Dilip Shantilal Sun Pharmaceutical , Ganorkar, Kirti Wardhaman Sun Pharmaceutical , Zala, Yashoraj Rupsinh. Sun Pharmaceutical Adv. R. , Dharmadhikari, Nitin B. Sun Pharmaceutical Adv. R. , Khanna, Satish C.
CPC分类号： A61K9/4808 , A61K9/1623 , A61K9/1652 , A61K9/2054 , A61K9/5047 , A61K9/5084 , A61K31/155 , A61K31/64 , A61K45/06 , A61K2300/00
摘要： The present invention provides to a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system, wherein the time of release of the two or more therapeutically active agents is designed to provide desired control on the disease condition. The present invention also provides a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system at a specified time prior to food intake by the patient. The present invention further provides a spaced drug delivery system that releases two or more antidiabetic agents at different times after oral administration, for the treatment of diabetes mellitus or conditions associated with diabetes mellitus. More particularly, the present invention provides a spaced drug delivery system that immediately releases one or more antidiabetic agents after oral administration of the system, and releases as a pulse one or more antidiabetic agents in a reliable manner at about a predetermined time after oral administration of the system.
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