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公开(公告)号:EP3763368A1
公开(公告)日:2021-01-13
申请号:EP20180303.8
申请日:2016-10-21
IPC分类号: A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/506 , A61K31/517 , A61K31/519 , A61P35/02
摘要: Described are methods of use of compounds that inhibit PIF-mediated substrate binding by PDK1, which are useful as inhibitors of cancer growth or proliferation that is RSK2-dependent or AKT-independent. Also described are compositions of such compounds for use in such methods of treating cancer.
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公开(公告)号:EP3364971A1
公开(公告)日:2018-08-29
申请号:EP16788389.1
申请日:2016-10-21
IPC分类号: A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/517 , A61K31/519 , A61P35/00 , A61P35/02
CPC分类号: A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/517 , A61K31/519
摘要: Described are methods of use of compounds that inhibit PIF-mediated substrate binding by PDK1, which are useful as inhibitors of cancer growth or proliferation that is RSK2-dependent or AKT-independent. Also described are compositions of such compounds for use in such methods of treating cancer.
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