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1.发明公开FUSED DIHYDRO-4H-PYRAZOLO[5,1-C][1,4]OXAZINYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS 审中-公开熔化的二氢-4H-吡唑并[5,1-C] [1,4]恶嗪化合物和类似物用于治疗中枢神经系统疾病
公开(公告)号：EP3256476A1
公开(公告)日：2017-12-20
申请号：EP16708260.1
申请日：2016-02-11
IPC分类号： C07D498/04 , C07D498/20 , A61K31/5365 , A61K31/537 , A61P25/00
CPC分类号： C07D498/04 , C07D498/14 , C07D498/20 , C07D498/22
摘要： and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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公开(公告)号：EP4046995A1
公开(公告)日：2022-08-24
申请号：EP22166538.3
申请日：2016-02-11
发明人： XIE, Linghong , JONES, Philip Glyn , SPEAR, Kerry L. , POWELL, Noel Aaron , HANANIA, Taleen G. , ALEXANDROV, Vadim
IPC分类号： C07D405/14 , C07D413/14 , C07D405/04 , C07D493/04 , A61K31/353 , A61K31/4025 , A61P25/00
摘要： Disclosed are compounds of Formula (I):
and pharmaceutically acceptable salts thereof, wherein A, R a , R 1 , R 2 , R 3 , R 4 , R 6 , w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.-
3.发明授权
公开(公告)号：EP3256476B1
公开(公告)日：2019-01-23
申请号：EP16708260.1
申请日：2016-02-11
IPC分类号： C07D498/04 , C07D498/14 , C07D498/20 , C07D498/22 , A61K31/5365 , A61K31/537 , A61P25/00
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公开(公告)号：EP3490607A1
公开(公告)日：2019-06-05
申请号：EP17835384.3
申请日：2017-07-28
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5.发明公开1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS 审中-公开用于治疗中枢神经系统疾病的1-HETEROCYCLYL异恶烷酰基化合物和类似物
公开(公告)号：EP3256466A1
公开(公告)日：2017-12-20
申请号：EP16708262.7
申请日：2016-02-11
发明人： XIE, Linghong , JONES, Philip Glyn , SPEAR, Kerry L. , POWELL, Noel Aaron , HANANIA, Taleen G. , ALEXANDROV, Vadim
IPC分类号： C07D405/14 , C07D413/14 , C07D405/04 , C07D493/04 , A61K31/353 , A61K31/4025 , A61P25/00
CPC分类号： C07D405/04 , C07D405/14 , C07D413/04 , C07D413/14 , C07D493/04
摘要： Disclosed are compounds of Formula (I): (Formula (I)) and pharmaceutically acceptable salts thereof, wherein A, R
a , R
1 , R
2 , R
3 , R
4 , R
6 , w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.-
6.发明公开
公开(公告)号：EP4006039A1
公开(公告)日：2022-06-01
申请号：EP21198192.3
申请日：2016-02-11
IPC分类号： C07D498/04 , C07D498/20 , A61K31/5365 , A61K31/537 , A61P25/00
摘要： Disclosed are compounds of Formula (I):
and pharmaceutically acceptable salts thereof, wherein Ring B, A 1 , A 2 , R 6 , w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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