公开(公告)号：EP1299359B1

公开(公告)日：2007-06-13

申请号：EP01938443.7

申请日：2001-06-14

申请人： Syngenta Limited

发明人： JONES, Raymond Vincent Heavon ,  STEWART, Alastair Iain Currie ,  WHITTON, Alan John ,  WHITE, Jennifer Ann C/O A J Whitton ,  FORRESTER, Julie ,  MURRAY, Joanne Emma ,  HAMILTON, Susan Thomson

IPC分类号： C07D213/64 ,  C07D215/22 ,  C07D277/68

CPC分类号： C07D213/64 ,  C07D215/227 ,  C07D277/68

摘要： A process for extracting from aqueous solution the alkali metal or calcium salt of a halo or haloalkyl substituted 2-hydroxypyridine, or a 2-hydroxyquinoline or 2-hydroxybenzothiazole which comprises contacting an aqueous alkaline or neutral solution of the alkali metal or calcium salt, in which is dissolved an alkali metal fluoride, chloride, bromide, hydroxide, sulphate, sulphite, cyanate, cyanide, thiocyanate, thiosulphate, sulphide, phosphate, hydrogen phosphate, carbonate, bicarbonate, borate, chlorate, hypochlorite, perchlorate, nitrite, chromate, dichromate or permanganate or calcium chloride, bromide, nitrate, nitrite, chlorate, hypochlorite, perchlorate, thiocyanate, thiosulphate, chromate, dichtromate or permanganate, with a partially water-miscible organic solvent so as to transfer aqueous solution of the alkali metal or calcium salt of the 2-hydroxypyridine, 2-hydroxyquinoline or 2-hydroxybenzothiazole into the solvent whilst retaining separate aqueous and solvent phases, and thereafter separating the solvent phase containing the alkali metal or calcium salt and water from the aqueous phase, the ratio of solvent to water in the separated solvent phase being from 0.5:1 to 10:1 w/w.

公开(公告)号：EP1299359A1

公开(公告)日：2003-04-09

申请号：EP01938443.7

申请日：2001-06-14

申请人： Syngenta Limited

发明人： JONES, Raymond Vincent Heavon ,  STEWART, Alastair Iain Currie ,  WHITTON, Alan John ,  WHITE, Jennifer Ann ,  FORRESTER, Julie ,  MURRAY, Joanne Emma ,  HAMILTON, Susan Thomson

IPC分类号： C07D213/64 ,  C07D215/22 ,  C07D277/68

CPC分类号： C07D213/64 ,  C07D215/227 ,  C07D277/68

摘要： A process for extracting from aqueous solution the alkali metal or calcium salt of a halo or haloalkyl substituted 2-hydroxypyridine, or a 2-hydroxyquinoline or 2-hydroxybenzothiazole which comprises contacting an aqueous alkaline or neutral solution of the alkali metal or calcium salt, in which is dissolved an alkali metal fluoride, chloride, bromide, hydroxide, sulphate, sulphite, cyanate, cyanide, thiocyanate, thiosulphate, sulphide, phosphate, hydrogen phosphate, carbonate, bicarbonate, borate, chlorate, hypochlorite, perchlorate, nitrite, chromate, dichromate or permanganate or calcium chloride, bromide, nitrate, nitrite, chlorate, hypochlorite, perchlorate, thiocyanate, thiosulphate, chromate, dichtromate or permanganate, with a partially water-miscible organic solvent so as to transfer aqueous solution of the alkali metal or calcium salt of the 2-hydroxypyridine, 2-hydroxyquinoline or 2-hydroxybenzothiazole into the solvent whilst retaining separate aqueous and solvent phases, and thereafter separating the solvent phase containing the alkali metal or calcium salt and water from the aqueous phase, the ratio of solvent to water in the separated solvent phase being from 0.5:1 to 10:1 w/w.

公开(公告)号：EP0840726B1

公开(公告)日：2001-10-10

申请号：EP96919956.1

申请日：1996-06-03

申请人： Syngenta Limited

发明人： WORTHINGTON, Paul Anthony, 4 Oakhurst ,  MUNNS, Gordon Richard, 22 Byron Road Earley ,  JONES, Raymond Vincent, Heavon, 26 Clarendon Road ,  STANDEN, Michael Charles Henry ,  RITCHIE, David John, 5 Yardley Place ,  FORRESTER, Julie

IPC分类号： C07D213/64

CPC分类号： C07D213/64

摘要： A process for the preparation of a 2-(6-substituted pyrid-2-yloxymethyl)phenylacetate which comprises treating a metal salt of a 6-substituted 2-pyridone with a compound L-CH2R where L is a leaving group and R is the residue of a 2-phenylacetate.