专利检索 ap:("Synthon Biopharmaceuticals B.V.") AND inv:"EPPINK, Michel Hendrikus Maria" 第 1 页

1.

发明公开
METHOD OF PURIFYING AN ANTIBODY 审中-公开
标题翻译： VERFAHREN ZUR REINIGUNG EINES防刺针

公开(公告)号：EP2864346A1

公开(公告)日：2015-04-29

申请号：EP12728608.6

申请日：2012-06-21

申请人： Synthon Biopharmaceuticals B.V.

发明人： KOKKE, Bastiaan Pieter Arian , VAN WIJK-BASTEN, Everdina Josephina Wilhelmina , DE BEIJER, Thomas Antonius Bernardus , EPPINK, Michel Hendrikus Maria , MARZÁ PÉREZ, Maria

IPC分类号： C07K1/36

CPC分类号： C07K1/36 , C07K1/18 , C07K1/34 , C07K16/065 , C07K16/32 , C07K2317/14

摘要： A method of purifying an antibody composition comprises application of anion exchange chromatography late in the purification process. An ultrafiltration/diafiltration-purified antibody composition is subjected to anion exchange chromatography (AEX) to form a pharmaceutically-pure antibody composition.

摘要翻译： 纯化抗体组合物的方法包括在纯化过程中晚期应用阴离子交换色谱法。将超滤/渗滤纯化的抗体组合物进行阴离子交换层析（AEX）以形成药物纯的抗体组合物。

2.

发明授权
METHOD OF PURIFYING AN ANTIBODY 有权

公开(公告)号：EP2864346B1

公开(公告)日：2018-10-17

申请号：EP12728608.6

申请日：2012-06-21

申请人： Synthon Biopharmaceuticals B.V.

发明人： KOKKE, Bastiaan Pieter Arian , VAN WIJK-BASTEN, Everdina Josephina Wilhelmina , DE BEIJER, Thomas Antonius Bernardus , EPPINK, Michel Hendrikus Maria , MARZÁ PÉREZ, Maria

IPC分类号： C07K1/36

CPC分类号： C07K1/36 , C07K1/18 , C07K1/34 , C07K16/065 , C07K16/32 , C07K2317/14

摘要： A method of purifying an antibody composition comprises application of anion exchange chromatography late in the purification process. An ultrafiltration/diafiltration-purified antibody composition is subjected to anion exchange chromatography (AEX) to form a pharmaceutically-pure antibody composition.