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1.发明公开COMPOSITION, METHOD AND KIT FOR POTENTIATING ANTITUMOR ACTIVITY AND FOR CURING TUMOR 失效组成，方法与仪器以强化抗肿瘤活性和肿瘤的治疗。
公开(公告)号：EP0543015A1
公开(公告)日：1993-05-26
申请号：EP92910345.5
申请日：1992-05-22
发明人： SHIRASAKA, Tetsuhiko , FUKUSHIMA, Masakazu 9-7, Sencho 2-chome , OHSHIMO, Hideyuki 10-28, Minamimachi , SHIMAMOTO, Yuji 9-11, Ogino-sato 2-chome
IPC分类号： A61K31/53
CPC分类号： A61K31/53 , A61K31/44 , A61K31/70 , A61K31/505 , A61K2300/00
摘要： A composition for potentiating the antitumor activity of tegafur and reducing the adverse effects, comprising a compound represented by general formula (I) wherein X represents halogen or cyano and oxonic acid or a pharmaceutically acceptable salt thereof, and a method and kit therefor; and a composition for curing tumors comprising tegafur, a compound represented by formula (I) and oxonic acid or a pharmaceutically acceptable salt thereof; and a method and kit therefor.
摘要翻译： 甲用于增强替加氟的抗肿瘤活性和减少的不利影响，包括由通式（I）worin X darstellt卤素或氰基和氧嗪酸或其药学上可接受的盐，和一种方法及其试剂盒表示的化合物的组合物; 以及用于治疗肿瘤，包括替加氟，由式（I）和氧嗪酸或其药学上可接受的盐表示的化合物的组合物; 及其方法和试剂盒。
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2.发明授权COMPOSITION, METHOD AND KIT FOR POTENTIATING ANTITUMOR ACTIVITY AND FOR CURING TUMOR 失效组成，方法与仪器以强化抗肿瘤活性和肿瘤的治疗
公开(公告)号：EP0543015B1
公开(公告)日：1998-11-11
申请号：EP92910345.5
申请日：1992-05-22
发明人： SHIRASAKA, Tetsuhiko , FUKUSHIMA, Masakazu 9-7, Sencho 2-chome , OHSHIMO, Hideyuki 10-28, Minamimachi , SHIMAMOTO, Yuji 9-11, Ogino-sato 2-chome
IPC分类号： A61K31/53
CPC分类号： A61K31/53 , A61K31/44 , A61K31/70 , A61K31/505 , A61K2300/00
摘要： A composition for potentiating the antitumor activity of tegafur and reducing the adverse effects, comprising a compound represented by general formula (I) wherein X represents halogen or cyano and oxonic acid or a pharmaceutically acceptable salt thereof, and a method and kit therefor; and a composition for curing tumors comprising tegafur, a compound represented by formula (I) and oxonic acid or a pharmaceutically acceptable salt thereof; and a method and kit therefor.
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