公开(公告)号：EP1757605A4

公开(公告)日：2007-12-19

申请号：EP05730330

申请日：2005-04-08

申请人： TAISHO PHARMA CO LTD

发明人： KUMAGAI TOSHIHITO ,  NAKAMURA TOSHIO ,  AMADA YURI ,  SEKIGUCHI YOSHINORI

IPC分类号： C07D471/04 ,  A61K31/407 ,  A61K31/4355 ,  A61K31/4365 ,  A61K31/437 ,  A61K31/55 ,  A61P25/00 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04

CPC分类号： C07D491/048 ,  C07D471/04 ,  C07D495/04

摘要： A cyclic amine compound represented by the following formula (1). It has potent adhesion inhibitory activity against an α2C receptor and is useful for the prevention or treatment of disorders attributable to the α2C receptor, e.g., diseases such as depression and anxiety. (Formula 1) (In the formula, X represents O, S, SO, SO2, NR2, etc.; R1 represents hydrogen, cyano, etc.; Ar1 and Ar2 each represents aryl, heteroaryl, etc.; ring B represents a benzene ring, etc.; n is an integer of 1 to 10; and p and q each is 1 or 2.)

公开(公告)号：EP2003131A4

公开(公告)日：2009-12-16

申请号：EP07740490

申请日：2007-03-30

申请人： TAISHO PHARMA CO LTD ,  NISSAN CHEMICAL IND LTD

发明人： OKUBO TAKETOSHI ,  KUMAGAI TOSHIHITO ,  ISHII TAKAAKI ,  NAKAMURA TOSHIO ,  ABE KUMI ,  AMADA YURI ,  ISHIZAKA TOMOKO ,  SUN XIANG-MIN ,  SEKIGUCHI YOSHINORI ,  SASAKO SHIGETADA ,  SHIMIZU TAKANORI ,  NAGATSUKA TAKAYUKI

IPC分类号： C07D401/12 ,  A61K31/4365 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/506 ,  A61K31/517 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/541 ,  A61P25/22 ,  A61P25/24

CPC分类号： C07D401/12