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    Polysulfate of cyclodextrin derivative and process for preparing the same
    3.
    发明公开
    Polysulfate of cyclodextrin derivative and process for preparing the same 失效
    多硫酸盐环糊精和Verfahren zu dessen Herstellung。

    公开(公告)号：EP0447171A2

    公开(公告)日：1991-09-18

    申请号：EP91302039.2

    申请日：1991-03-12

    申请人： TANABE SEIYAKU CO., LTD.

    发明人： Kurita, Hironori ,  Moriya, Tamon ,  Otake, Toru ,  Mori, Haruyo ,  Morimoto, Motoko

    IPC分类号： C08B37/16 ,  A61K31/735

    CPC分类号： C08B37/0012

    摘要： A polysulfate of a cyclodextrin in which at least one of 6 to 8 D-glucose units constituting the cyclodextrin has been replaced by a unit represented by Formula(1):

    wherein R is a group represented by the formula:

    where R¹ to R⁷ are defined in the specification, which have an excellent antiretrovirus activity, particularly an excellent proliferation-inhibiting activity against HIV.

    摘要翻译： 其中构成环糊精的6〜8个D-葡萄糖单元中的至少一个已被式（1）表示的单元替代为环糊精的多硫酸盐：其中R为下式表示的基团：CHEM> 其中R 1至R 7在说明书中定义，其具有优异的抗逆转录病毒活性，特别是对HIV的优异增殖抑制活性。

    Polysulfate of beta-cyclodextrin derivative and process for preparing the same
    5.
    发明公开
    Polysulfate of beta-cyclodextrin derivative and process for preparing the same 失效
    聚硫酸酯β-环糊精和Verfahren zu dessen Herstellung。

    公开(公告)号：EP0531016A2

    公开(公告)日：1993-03-10

    申请号：EP92307559.2

    申请日：1992-08-19

    申请人： TANABE SEIYAKU CO., LTD.

    发明人： Moriya, Tamon ,  Kurita, Hironori ,  Otake, Toru ,  Mori, Haruyo ,  Morimoto, Motoko

    IPC分类号： C08B37/16 ,  A61K31/735 ,  C08B37/00

    CPC分类号： C08B37/0012

    摘要： Disclosed is a polysulfate of a β-cyclodextrin in which at least one of 7 D-glucose units constituting the β-cyclodextrin is a unit represented by the formula (I - a):

       wherein R¹ is an alkyl group having 1 to 8 carbon atoms, a lower alkyl group having a substituent(s) or a lower alkenyl group,
    or a salt thereof, which has excellent antiretrovirus activity and is useful as an antiretrovirus agent.

    摘要翻译： 公开了β-环糊精的多硫酸盐，其中构成β-环糊精的7个D-葡萄糖单元中的至少一个是由式（I-a）表示的单元：其中R 1是烷基 具有1至8个碳原子，具有取代基的低级烷基或低级链烯基，或其盐具有优异的抗逆转录病毒活性并且可用作抗逆转录病毒剂。