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1.发明授权BIS-(N,N'-BIS-(2-HALOETHYL)AMINO) PHOSPHORAMIDATES AS ANTITUMOR AGENTS 有权双（N，N'-双（2-卤代乙基）氨基）磷酸酯作为抗肿瘤剂
公开(公告)号：EP1278759B1
公开(公告)日：2005-12-21
申请号：EP01935025.5
申请日：2001-05-02
申请人： TELIK, INC.
发明人： HERR, Jason, R. , LUM, Robert, T. , SCHOW, Steven, R. , MENG, Fanying , KOZLOWSKI, Michael, R. , ZHICHKIN, Pavel
IPC分类号： C07F9/24 , A61K31/664 , A61P35/04
CPC分类号： C07F9/2458 , C07F9/2408
摘要： The present invention relates to chemical compounds, methods of treatment, pharmaceutical compositions, and processes for their preparation. The compounds possess anti-tumor activities or are capable of being modified to have anti-tumor activities, and therefore, this invention particularly relates to the use of the compounds in methods for the treatment of tumors and especially for the treatment of cancer, as well as to the processes for their preparation.
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2.发明公开BIS-(N,N'-BIS-(2-HALOETHYL)AMINO) PHOSPHORAMIDATES AS ANTITUMOR AGENTS 有权双（N，N'-双（2-卤代乙基）氨基）磷酸酯作为抗肿瘤剂
公开(公告)号：EP1278759A1
公开(公告)日：2003-01-29
申请号：EP01935025.5
申请日：2001-05-02
申请人： TELIK, INC.
发明人： HERR, Jason, R. , LUM, Robert, T. , SCHOW, Steven, R. , MENG, Fanying , KOZLOWSKI, Michael, R. , ZHICHKIN, Pavel
IPC分类号： C07F9/24 , A61K31/664 , A61P35/04
CPC分类号： C07F9/2458 , C07F9/2408
摘要： The present invention relates to chemical compounds, methods of treatment, pharmaceutical compositions, and processes for their preparation. The compounds possess anti-tumor activities or are capable of being modified to have anti-tumor activities, and therefore, this invention particularly relates to the use of the compounds in methods for the treatment of tumors and especially for the treatment of cancer, as well as to the processes for their preparation.
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