专利检索 ap:("TELIK, INC.") AND inv:"MANCHEM, Prasad V. V. S. V." 第 1 页

1.

发明公开
INSULIN RECEPTOR ACTIVATORS FOR THE TREATMENT OF METABOLIC DISORDERS IN HUMANS RESULTING FROM TREATMENT OF HIV INFECTION WITH HIV PROTEASE INHIBITORS 审中-公开
标题翻译：胰岛素受体激活剂治疗代谢性疾病的HIV感染了HIV蛋白酶抑制剂的治疗引起的

公开(公告)号：EP1355698A2

公开(公告)日：2003-10-29

申请号：EP01980019.2

申请日：2001-10-10

申请人： TELIK, INC.

发明人： MANCHEM, Prasad V. V. S. V. , LUM, Robert, T. , SCHOW, Steven, R.

IPC分类号： A61P3/10 , A61P5/50 , A61K31/655 , A61K31/195 , A61K31/185

CPC分类号： A61K31/19 , A61K31/17 , A61K31/18 , A61K31/185 , A61K31/195 , A61K31/655

摘要： The present invention comprises the use of insulin receptor activating compounds, optionally in conjunction with insulin, for the treatment of HIV protease inhibitor-induced metabolic disorders. Any insulin receptor activating compounds is suitable for the practice of the invention. In addition, preferred compounds are disclosed. Methods of treating a person suffering from HIV protease inhibitor-induced metabolic disorders such as lipodystrophy, hypertriglyceridemia, insulin resistance, hyperglycemia, diabetes and ketoacidosis are also provided.