公开(公告)号：EP0166998B1

公开(公告)日：1991-05-08

申请号：EP85106929.4

申请日：1985-06-04

申请人： TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION

发明人： Takemura, Naoto ,  Tanabe, Susumu

IPC分类号： A61L29/00 ,  C08J7/04

CPC分类号： A61L29/085 ,  Y10T428/1352 ,  Y10T428/1379 ,  Y10T428/1393 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31725 ,  Y10T428/3188

公开(公告)号：EP0166998A2

公开(公告)日：1986-01-08

申请号：EP85106929.4

申请日：1985-06-04

申请人： TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION

发明人： Takemura, Naoto ,  Tanabe, Susumu

IPC分类号： A61L29/00 ,  C08J7/04

CPC分类号： A61L29/085 ,  Y10T428/1352 ,  Y10T428/1379 ,  Y10T428/1393 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31725 ,  Y10T428/3188

摘要： A medical instrument comprises a substrate which has at least on its surface a reactive functional group covalently bonded with a water-soluble polymer or derivative thereof, whereby said surface has lubricity when wetted. The water-soluble polymer is a cellulosic polymer, maleic anhydride polymer, polyacrylamide or water-soluble nylon.
The medical instrument is prepared by treating a substrate with a solution of a compound having a reactive functional group to form an undercoat so that the reactive functional group is present at least on the substrate surface, and then treating the substrate with a water-soluble polymer or derivative thereof to covalently bond the reactive functional group with the water-soluble polymer to thereby form a coat of the water-soluble polymer on the undercoat and optionally, contacting the treated substrate with water.

公开(公告)号：EP0166998A3

公开(公告)日：1987-08-05

申请号：EP85106929

申请日：1985-06-04

申请人： TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION

发明人： Takemura, Naoto ,  Tanabe, Susumu

IPC分类号： A61L29/00 ,  C08J07/04

CPC分类号： A61L29/085 ,  Y10T428/1352 ,  Y10T428/1379 ,  Y10T428/1393 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31725 ,  Y10T428/3188

摘要： A medical instrument comprises a substrate which has at least on its surface a reactive functional group covalently bonded with a water-soluble polymer or derivative thereof, whereby said surface has lubricity when wetted. The water-soluble polymer is a cellulosic polymer, maleic anhydride polymer, polyacrylamide or water-soluble nylon. The medical instrument is prepared by treating a substrate with a solution of a compound having a reactive functional group to form an undercoat so that the reactive functional group is present at least on the substrate surface, and then treating the substrate with a water-soluble polymer or derivative thereof to covalently bond the reactive functional group with the water-soluble polymer to thereby form a coat of the water-soluble polymer on the undercoat and optionally, contacting the treated substrate with water.