公开(公告)号：EP1742938A1

公开(公告)日：2007-01-17

申请号：EP04795454.0

申请日：2004-10-15

申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD.

发明人： ETINGER, Marina, Yu ,  NIDDAM-HILDESHEIM, Valerie ,  FEDOTEV, Boris ,  DOLITZKY, Ben-Zion

IPC分类号： C07D403/10

CPC分类号： C07D403/10 ,  Y02P20/55

摘要： The present invention is directed to the preparation of substantially pure candesartan cilexetil by the deprotection of trityl candesartan cilexetil and crystallization and/or recrystallization of candesartan cilexetil.

公开(公告)号：EP1713795A2

公开(公告)日：2006-10-25

申请号：EP05713277.1

申请日：2005-02-11

申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD.

发明人： ETINGER, Marina, Yu ,  FEDOTEV, Boris ,  KOLTAI, Tamas ,  KURGAN, Ziv ,  MALACHI, Omer

IPC分类号： C07D403/10

CPC分类号： C07D403/10

摘要： Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable excipient with at least one candesartan cilexetil form of the invention.