公开(公告)号：EP3077822A4

公开(公告)日：2017-08-02

申请号：EP14868385

申请日：2014-12-02

申请人： THE FUND FOR MEDICAL RES DEV OF INFRASTRUCTURE AND HEALTH SERVICES - BNAI ZION MEDICAL CENTER ,  TECHNION RES & DEV FOUNDATION

发明人： VADASZ ZAHAVA ,  HALACHMI SAREL ,  RUBINSTEIN JACOB ,  NATIV OFER ,  TOUBI ELIAS

IPC分类号： G01N33/574

CPC分类号： G01N33/57407 ,  G01N33/57434 ,  G01N33/57438 ,  G01N33/57484 ,  G01N2333/4703 ,  G01N2333/4704 ,  G01N2800/52

摘要： The present invention is directed to methods and kits useful for diagnosis and/or prognosis of urothelial cancer in a subject. The present invention further relates to methods of assessing severity of cancer and methods of determining efficacy of a treatment for cancer. The methods and kits of the invention comprise determining the levels of semaphorin 3A in a biological sample of a subject.

摘要翻译： 本发明涉及可用于受试者中尿路上皮癌的诊断和/或预后的方法和试剂盒。 本发明进一步涉及评估癌症严重性的方法和确定癌症治疗功效的方法。 本发明的方法和试剂盒包括测定受试者的生物样品中的信号素3A的水平。