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公开(公告)号:EP1817056B1
公开(公告)日:2014-08-13
申请号:EP05851439.9
申请日:2005-11-08
申请人: THE GENERAL HOSPITAL CORPORATION
发明人: SCADDEN, David, T. , ADAMS, Gregor , KORNENBERG, Henry , CALVI, Laura, M.
IPC分类号: A61K38/29 , C07K14/635 , C12N5/00 , C12N5/02 , G01N33/53
CPC分类号: A61K38/29 , C12N5/0647 , C12N2501/37 , C12N2502/1394
公开(公告)号:EP1817056A2
公开(公告)日:2007-08-15
IPC分类号: A61K39/395 , A61K35/14
摘要: The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.
摘要翻译: 本发明涉及通过激活相邻细胞中的PTH / PTHrP受体来操纵造血干细胞或祖细胞,间充质干细胞,上皮干细胞,神经干细胞和相关产物的方法。