公开(公告)号：EP1227789A1

公开(公告)日：2002-08-07

申请号：EP00977112.2

申请日：2000-11-10

申请人： THE PROCTER & GAMBLE COMPANY

发明人： GLANDORF, William, Michael ,  DIXON, Cloyd, Jr. ,  JACOBS, David, Scott ,  WALDEN, Gary, Lyle ,  WIREKO, Fred, Christian

IPC分类号： A61K7/16

CPC分类号： A61Q11/00 ,  A61K8/02 ,  A61K8/19 ,  A61K8/21 ,  A61K8/365 ,  A61K2800/58 ,  A61K2800/88

摘要： The present invention relates to dual phase oral compositions providing effective antimicrobial activity for reducing plaque and gingivitis. One of the phases of the dual phase composition will contain stannous. The stannous phase comprises a stannous ion source, a fluoride ion source, and a gluconate salt. The stannous phase is essentially free of either an abrasive polishing material or chloride ions. The stannous phase containing phase inhibits the formation of a stannous chloro gluconate complex. The present invention also provides a method for effective delivery of stannous-containing compositions.

公开(公告)号：EP1227789B1

公开(公告)日：2004-09-22

申请号：EP00977112.2

申请日：2000-11-10

申请人： THE PROCTER & GAMBLE COMPANY

发明人： GLANDORF, William, Michael ,  DIXON, Cloyd, Jr. ,  JACOBS, David, Scott ,  WALDEN, Gary, Lyle ,  WIREKO, Fred, Christian

IPC分类号： A61K7/16

CPC分类号： A61Q11/00 ,  A61K8/02 ,  A61K8/19 ,  A61K8/21 ,  A61K8/365 ,  A61K2800/58 ,  A61K2800/88