专利检索 ap:("THE UNIVERSITY OF MARYLAND AT BALTIMORE") AND inv:"FRANKLIN, Renty, B." 第 1 页

1.

发明公开
HUMAN ZIP1, ZINC AND CITRATE FOR PROSTATE CANCER SCREENING 审中-公开
标题翻译：人类ZIP1，前列腺癌研究锌和柠檬酸

公开(公告)号：EP1977248A2

公开(公告)日：2008-10-08

申请号：EP07762499.7

申请日：2007-01-23

申请人： THE UNIVERSITY OF MARYLAND AT BALTIMORE

发明人： FRANKLIN, Renty, B. , COSTELLO, Leslie, C.

IPC分类号： G01N33/574 , C12N5/06 , C12N5/16

CPC分类号： C12Q1/6886 , C12Q2600/158 , Y10T436/201666

摘要： The present invention provides methods of detecting prostate cancer employing biomarkers, including hZIPl, zinc and citrate. Also provided are antibodies to detect hZIPl protein or peptides and an expression vector comprising a genetic sequence effective to increase uptake of zinc into a prostate cell upon expression thereof. Furthermore, methods of treating prostate cancer and of increasing uptake of zinc into a prostate cell are provided.