公开(公告)号：EP3456737A1

公开(公告)日：2019-03-20

申请号：EP17191988.9

申请日：2017-09-19

申请人： TILLOTTS PHARMA AG

发明人： FURRER, Esther

IPC分类号： C07K16/24

摘要： The present invention relates to antibodies which bind to TNFα and exhibit modified FcRn-binding. The antibodies of the invention have good effector functions and/or pharmacokinetic properties.

公开(公告)号：EP3456739A1

公开(公告)日：2019-03-20

申请号：EP17191990.5

申请日：2017-09-19

申请人： TILLOTTS PHARMA AG

发明人： FURRER, Esther

IPC分类号： C07K16/24 ,  A61P17/02 ,  A61P37/00

摘要： The present invention relates to an antibody comprising a TNFα-binding domain and an Fc region for use in the treatment of wounds.

公开(公告)号：EP3456736A1

公开(公告)日：2019-03-20

申请号：EP17191987.1

申请日：2017-09-19

申请人： TILLOTTS PHARMA AG

发明人： FURRER, Esther

IPC分类号： C07K16/24

摘要： The present invention relates to antibodies which bind to TNFα and comprise a modified Fc region. The antibodies of the invention have improved resistance against proteolytic degradation and good effector functions and/or pharmacokinetic properties.

公开(公告)号：EP3456738A1

公开(公告)日：2019-03-20

申请号：EP17191989.7

申请日：2017-09-19

申请人： TILLOTTS PHARMA AG

发明人： FURRER, Esther

IPC分类号： C07K16/24

摘要： The present invention relates to antibodies which bind to TNFα and exhibit modified FcRn-binding. The antibodies of the invention have good effector functions and/or pharmacokinetic properties.