专利检索 ap:("TOYAMA CHEMICAL CO LTD") AND inv:"MIYAJIMA MIKAKO" 第 1 页

1.

发明公开
NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME 审中-公开
标题翻译：螺环化合物或其盐和自身免疫预防或治疗剂和含有AP-1抑制剂

公开(公告)号：EP1076056A4

公开(公告)日：2002-08-14

申请号：EP99918266

申请日：1999-04-28

申请人： TOYAMA CHEMICAL CO LTD

发明人： CHAKI HISAAKI , AIKAWA YUKIHIKO , MIYAJIMA MIKAKO , TAKAKURA TADAKAZU , NISHIO MORIHIRO , KURODA HIROSHI , TANAKA KEIICHI , KAJITA TETSUYA , HIRONO SHUICHI , SHIOZAWA SHUNICHI

IPC分类号： A61K38/00 , C07D277/60 , C07D417/04 , C07D417/06 , C07D417/08 , C07D417/12 , C07D513/10 , C07K5/078 , A61K31/425 , A61K38/04 , C07K5/04

CPC分类号： C07D277/60 , A61K38/00 , C07D417/04 , C07D417/06 , C07D417/08 , C07D417/12 , C07D513/10 , C07K5/06139

摘要： Spiro compounds represented by general formula (I), wherein A, R?2, R3, R4, R5, R6¿ and n are each as defined in the specification; which exert an AP-1 activity inhibitory effect. Owing to this effect, these compounds are useful as remedies/preventives for autoimmune diseases which inhibit the expression of various genes and show little side effect.