公开(公告)号：EP0679092B1

公开(公告)日：1999-04-28

申请号：EP95902487.8

申请日：1994-11-09

申请人： TREGA BIOSCIENCES, INC.

发明人： SUTO, Mark, J. ,  GIRTEN, Beverly, E. ,  HOUGHTEN, Richard, A. ,  LOULLIS, Costas, C. ,  TUTTLE, Ronald, R.

IPC分类号： C07K5/02 ,  C07K7/52 ,  C07K9/00 ,  A61K38/08

CPC分类号： A61K38/08 ,  C07K5/1024 ,  C07K14/68 ,  C07K14/685 ,  C07K14/695

摘要： The present invention provides novel cytokine restraining agents, which limit or control the biological activity of cytokines. The invention also provides pharmaceutical compositions comprising a cytokine restraining peptide and methods of administering the pharmaceutical composition to a subject. The invention further provides methods for using the novel peptides to restrain cytokine activity in a subject.