专利检索 ap:("TRUSTEES OF TUFTS UNIVERSITY" OR "UNIVERSITY OF MASSACHUSETTS LOWELL") AND inv:"KAPLAN, David, L." 第 1 页

1.

发明公开
EMULSAN AND EMULSAN ANALOGS IMMUNIZATION FORMULATIONS AND USE 审中-公开
标题翻译： Emulsan和免疫EMULSANANALOGEN含组合物及其

公开(公告)号：EP1159002A2

公开(公告)日：2001-12-05

申请号：EP00913751.4

申请日：2000-03-03

申请人： TRUSTEES OF TUFTS UNIVERSITY , UNIVERSITY OF MASSACHUSETTS LOWELL

发明人： KAPLAN, David, L. , FUHRMAN, Juliet , GROSS, Richard, A.

IPC分类号： A61K39/39 , C12N15/01

CPC分类号： C12P19/04 , A61K35/74 , A61K39/00 , A61K39/39 , A61K2039/55583 , C12P7/64 , A61K2300/00

摘要： Immunization formulations comprising an antigen and an emulsan or emulsan analog are formed and can be administered to a host. The emulsan or emulsan analog is an adjuvant in the immunization formulation. The emulsan or emulsan analog is secreted from Acinetobacter calcoaceticus. In particular, the emulsan or emulsan analog is secreted from Acinetobacter calcoaceticus RAG-1. The emulsan analog is produced and secreted from Acinetobacter calcoaceticus cultured in the presence of varying fatty acid sources. The emulsan analog is also produced and secreted from mutants of Acinetobacter calcoaceticus, such as transposon mutants of Acinetobacter calcoaceticus RAG-1.