公开(公告)号：EP0594890A1

公开(公告)日：1994-05-04

申请号：EP92118620.1

申请日：1992-10-30

申请人： TSUMURA & CO.

发明人： Tanaka, Masahide ,  Wakamatsu, Takeshi ,  Mitsuhashi, Hiroshi ,  Sato, Toshitsugu, c/oTsumura Co.

IPC分类号： C07D307/93 ,  C07D317/70 ,  C07D498/14 ,  C07C43/21 ,  C07C69/757 ,  C07C43/205 ,  C07D493/04 ,  A61K31/365 ,  A61K31/215

CPC分类号： C07D493/04 ,  C07C69/00 ,  C07C2603/00 ,  C07D307/93 ,  C07D317/70

摘要： Polycyclic compounds (I) can be prepared in accordance with the following reaction formula:

wherein R₁-R₈ each represents a hydrogen atom, a hydroxyl group, an alkoxyl group or a substituted or unsubstituted benzyloxy group or neighboring two groups of R₁-R₈ are coupled together to form an alkylenedioxy group; and A is an alkylene group which may be substituted by one or more alkoxycarbonyl groups, an alkenylene group which may be substituted by one or more alkoxycarbonyl groups, or a group represented by any one of the following formulas:

摘要翻译： 多环化合物（I）可以根据以下反应式制备：其中R 1 -R 8各自表示氢原子，羟基，烷氧基或取代或未取代的苄氧基或相邻的两个R1- R8结合在一起形成亚烷基二氧基; A可以被一个或多个烷氧基羰基取代的亚烷基，可以被一个或多个烷氧基羰基取代的亚烯基，或由下式中的任何一个表示的基团：