公开(公告)号：EP1005453B1

公开(公告)日：2004-10-27

申请号：EP98939384.8

申请日：1998-08-13

申请人： TULARIK, INC.

发明人： MEDINA, Julio, Cesar ,  CLARK, David, Louis ,  FLYGARE, John, A. ,  ROSEN, Terry, J. ,  SHAN, Bei

IPC分类号： C07C311/21 ,  A61K31/18

CPC分类号： C07C311/21

摘要： The invention provides compounds, compositions and methods relating to novel electrophilic aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, psoriasis, vascular restenosis, infections, atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of general Formula (I).

公开(公告)号：EP1005453A1

公开(公告)日：2000-06-07

申请号：EP98939384.8

申请日：1998-08-13

申请人： TULARIK, INC.

发明人： MEDINA, Julio, Cesar ,  CLARK, David, Louis ,  FLYGARE, John, A. ,  ROSEN, Terry, J. ,  SHAN, Bei

IPC分类号： C07C311/21 ,  A61K31/18

CPC分类号： C07C311/21

摘要： The invention provides compounds, compositions and methods relating to novel electrophilic aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, psoriasis, vascular restenosis, infections, atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of general Formula (I).