专利检索 ap:("Talecris Biotherapeutics, Inc.") AND inv:"ZIMMERMAN, Thomas, P." 第 1 页

1.

发明公开
COMPOSITION, METHOD AND KIT FOR PREPARING PLASMIN 审中-公开
标题翻译：组成，方法和试剂盒用于制备纤溶酶

公开(公告)号：EP2297317A2

公开(公告)日：2011-03-23

申请号：EP09759358.6

申请日：2009-06-03

申请人： Talecris Biotherapeutics, Inc.

发明人： KOEPF, Edward , ZIMMERMAN, Thomas, P.

IPC分类号： C12N9/68 , C12P21/06

CPC分类号： C12N11/10 , C07K14/3153 , C12N9/6435 , C12Y304/21007

摘要： A streptokinase immobilized on a surface, in particular an immobilized plasmin- resistant streptokinase, and compositions, methods and kits of utilizing same for preparing plasmin are provided.

2.

发明授权
REVERSIBLY INACTIVATED ACIDIFIED PLASMIN 有权
标题翻译：可逆灭活酸化纤溶酶

公开(公告)号：EP1232252B1

公开(公告)日：2009-05-13

申请号：EP00990910.2

申请日：2000-11-13

申请人： Talecris Biotherapeutics, Inc.

发明人： ZIMMERMAN, Thomas, P. , NOVOKHATNY, Valery , JIANG, Shan , COLANDENE, James

IPC分类号： C12N9/48 , C12N9/72 , C12N9/68 , C12N9/96 , C12N9/76 , A61K38/48 , A61K9/50

CPC分类号： C12N9/6435 , A61K38/4833 , A61K38/484 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/183 , A61K47/26 , C12N9/96 , C12N9/99 , C12Y304/21007

摘要： The present invention provides a fibrinolytic composition useful as a therapeutic for administration to a patient having a thrombotic occlusion. In one aspect of the present invention, the fibrinolytic composition comprises a reversibly inactivated acidified serine protease substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent. In another aspect of the invention, the fibrinolytic composition of the present invention comprises a reversibly inactivated acidified plasmin substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent.

3.

发明授权
METHOD OF THROMBOLYSIS BY LOCAL DELIVERY OF REVERSIBLY INACTIVATED ACIDIFIED PLASMIN 有权
标题翻译：方法溶栓治疗以局部治疗具有可逆性灭活酸化纤溶酶

公开(公告)号：EP1232251B1

公开(公告)日：2007-08-15

申请号：EP00978572.6

申请日：2000-11-13

申请人： Talecris Biotherapeutics, Inc.

发明人： NOVOKHATNY, Valery, B. , JESMOK, Gary, J. , LANDSKRONER, Kyle, A. , TAYLOR, Kathryn, K. , ZIMMERMAN, Thomas, P.

IPC分类号： C12N9/48 , C12N9/72 , C12N9/68 , A61K38/48

CPC分类号： C12N9/6435 , A61K38/4833 , A61K38/484 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/183 , A61K47/26 , C12N9/96 , C12N9/99 , C12Y304/21007

摘要： The present invention provides a fibrinolytic composition useful as a therapeutic for administration to a patient having a thrombotic occlusion. In one aspect of the present invention, the fibrinolytic composition comprises a reversibly inactivated acidified serine protease substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent. In another aspect of the invention, the fibrinolytic composition of the present invention comprises a reversibly inactivated acidified plasmin substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent.

4.

发明公开
COMPOSITIONS, METHODS AND KITS FOR PREPARING PLASMINOGEN; AND PLASMIN PREPARED THEREFROM 有权
标题翻译：用于制备疟原虫的组合物，方法和试剂盒; 和由此制备的血浆蛋白

公开(公告)号：EP2403865A2

公开(公告)日：2012-01-11

申请号：EP10749193.8

申请日：2010-03-02

申请人： Talecris Biotherapeutics, Inc.

发明人： KOEPF, Edward , LINDSAY, Myles , SILVERSTEIN, Rebecca , HUNT, Jennifer, A. , REBBEOR, James , ZIMMERMAN, Thomas, P. , MILLER, Charles , CARONNA, Anthony , STOKES, Kenya

IPC分类号： C07K1/18 , C12N9/50 , C12N15/57

CPC分类号： C12N9/6435 , C12Y304/21007

摘要： Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.

摘要翻译： 提供了用于制备纤溶酶原，特别是重组纤溶酶原的组合物和方法，以及使用它们制备纤溶酶的组合物和方法。