公开(公告)号：EP2043434A2

公开(公告)日：2009-04-08

申请号：EP06848431.0

申请日：2006-12-01

申请人： The Arizona Board Of Regents On Behalf Of The University of Arizona

发明人： JOENS, Lynn A. ,  THEORET, James R. ,  REESER, Ryan J. ,  LAW, Bibiana

IPC分类号： A01N37/18 ,  C12N1/20 ,  G01N33/53

CPC分类号： G01N33/56922 ,  G01N2333/205 ,  G01N2469/10 ,  G01N2469/20

摘要： The present disclosure provides coding and amino acid sequences for a Campylobacter jejuni pilus protein (and from other species as well). This protein, when administered to a human or animal, elicits the expression of an immune response to Campylobacter jejuni, with the result that colonization and/or infection by this organism is reduced. Recombinant protein or biofilm material comprising the pilus protein is formulated into immunogenic compositions, especially for mucosal administration. Thus, the present invention provides methods for improvement of the microbial quality of food products including poultry, eggs, meat and dairy products, and indirectly of plant foods that may come in contact with agricultural waste, either from fertilization or from irrigation water.