公开(公告)号：EP2702146A2

公开(公告)日：2014-03-05

申请号：EP12775920.7

申请日：2012-04-27

申请人： The Board of Trustees of the Leland Stanford Junior University ,  Department of Veterans Affairs

发明人： ROBINSON, William H. ,  TAN, Yann Chong ,  SOKOLOVE, Jeremy

IPC分类号： C12N5/10

CPC分类号： C12N15/1065 ,  C07K16/00 ,  C07K16/1242 ,  C07K16/1271 ,  C07K2317/21 ,  C07K2317/76 ,  G01N33/6854 ,  G01N2458/10 ,  G01N2500/00

摘要： Disclosed herein are compositions and methods for sequencing, analyzing, and utilizing samples such as single samples. Also disclosed herein are compositions and methods for matching together two or more sequences from a sample. Also disclosed herein are compositions and methods for expressing and screening molecules of interest.

公开(公告)号：EP2702146B1

公开(公告)日：2018-11-28

申请号：EP12775920.7

申请日：2012-04-27

申请人： The Board of Trustees of the Leland Stanford Junior University ,  Department of Veterans Affairs

发明人： ROBINSON, William H. ,  TAN, Yann Chong ,  SOKOLOVE, Jeremy

IPC分类号： C12N5/10 ,  C07K16/12 ,  C07K16/00 ,  G01N33/68

CPC分类号： C12N15/1065 ,  C07K16/00 ,  C07K16/1242 ,  C07K16/1271 ,  C07K2317/21 ,  C07K2317/76 ,  G01N33/6854 ,  G01N2458/10 ,  G01N2500/00

摘要： Disclosed herein are compositions and methods for sequencing, analyzing, and utilizing samples such as single samples. Also disclosed herein are compositions and methods for matching together two or more sequences from a sample. Also disclosed herein are compositions and methods for expressing and screening molecules of interest.

公开(公告)号：EP3415619A3

公开(公告)日：2019-01-02

申请号：EP18180597.9

申请日：2012-04-27

申请人： The Board of Trustees of the Leland Stanford Junior University ,  Department of Veterans Affairs

发明人： ROBINSON, William H. ,  TAN, Yann Chong ,  SOKOLOVE, Jeremy

IPC分类号： C12N5/10 ,  C07K16/12 ,  C07K16/00 ,  G01N33/68

摘要： Disclosed herein are compositions and methods for sequencing, analyzing, and utilizing samples such as single samples. Also disclosed herein are compositions and methods for matching together two or more sequences from a sample. Also disclosed herien are compositions and methods for expressing and screening molecules of interest.

公开(公告)号：EP2967062A1

公开(公告)日：2016-01-20

申请号：EP14763776.3

申请日：2014-03-14

申请人： The Board of Trustees of The Leland Stanford Junior University ,  Department of Veterans Affairs

发明人： ROBINSON, William H. ,  SOKOLOVE, Jeremy ,  WANG, Qian

IPC分类号： A01N43/54 ,  A61K31/505

CPC分类号： A61K31/4706 ,  A61K31/40 ,  A61K45/06 ,  G01N33/6893 ,  A61K2300/00

摘要： Compositions and methods are provided for inhibiting or treating the early and established stages of inflammatory diseases by administration of an effective dose of the desethylhydroxychloroquine (DHCQ). A benefit of the methods is the ability to deliver a dose of agent that is effective in treating inflammation while sparing the individual from retinal toxicity.

摘要翻译： 提供了通过施用有效剂量的去乙基羟基氯喹（DHCQ）来抑制或治疗炎性疾病的早期和确定阶段的组合物和方法。 这些方法的好处是能够递送一剂有效治疗炎症的药剂，同时避免个体出现视网膜毒性。