CYTOKINE-CHITOSAN BIOCONJUGATES AND METHODS OF USING THE SAME
    2.
    发明公开
    CYTOKINE-CHITOSAN BIOCONJUGATES AND METHODS OF USING THE SAME 审中-公开
    细胞因子 - 壳聚糖生物复合物及其使用方法

    公开(公告)号:EP3166406A1

    公开(公告)日:2017-05-17

    申请号:EP15800453.1

    申请日:2015-06-01

    IPC分类号: A01N43/04 A61K31/715

    摘要: Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders. The compositions are especially suitable for localized delivery and may allow for intratamoral delivery and treatment of cancers or stimulation of an immune response to a co-administered antigen.

    摘要翻译: 本文提供了包含与细胞因子或生长因子共价连接的壳聚糖的组合物。 该组合物可用于生产药物组合物并可用于治疗各种疾病或病症的方法中。 该组合物特别适用于局部递送,并且可以允许肿瘤内的递送递送和治疗或刺激对共同施用的抗原的免疫应答。