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公开(公告)号:EP3166406B1
公开(公告)日:2020-08-05
申请号:EP15800453.1
申请日:2015-06-01
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2.
公开(公告)号:EP3166406A1
公开(公告)日:2017-05-17
申请号:EP15800453.1
申请日:2015-06-01
发明人: ZAHAROFF, David, A. , THALLAPURANAM, Suresh, Kumar , JAYANTHI, Srinivas , KOPPOLU, Bhanu, Prasanth , SMITH, Sean, C.
IPC分类号: A01N43/04 , A61K31/715
摘要: Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders. The compositions are especially suitable for localized delivery and may allow for intratamoral delivery and treatment of cancers or stimulation of an immune response to a co-administered antigen.
摘要翻译: 本文提供了包含与细胞因子或生长因子共价连接的壳聚糖的组合物。 该组合物可用于生产药物组合物并可用于治疗各种疾病或病症的方法中。 该组合物特别适用于局部递送,并且可以允许肿瘤内的递送递送和治疗或刺激对共同施用的抗原的免疫应答。
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